Cell
2023 Generating parallel representations of position and identity in the olfactory system Ricca's factors as mobile proteinaceous effectors of electrical signaling Sparse and stereotyped encoding implicates a core glomerulus for ant alarm behavior 2022 A male-derived nonribosomal peptide pheromone controls female schistosome development Scent of a human: The mosquito olfactory system defies dogma to ensure attraction to humans 2021 Evolutionary assembly of cooperating cell types in an animal chemical defense system 2020 Genomes of the Banyan Tree and Pollinator Wasp Provide Insights into Fig-Wasp Coevolution 2019 Limbic Neurons Shape Sex Recognition and Social Behavior in Sexually Naive Males Engineering a Model Cell for Rational Tuning of GPCR Signaling A Jasmonate Signaling Network Activates Root Stem Cells and Promotes Regeneration 2018 Multisensory Logic of Infant-Directed Aggression by Males Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control 2017 An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants orco Mutagenesis Causes Loss of Antennal Lobe Glomeruli and Impaired Social Behavior in Ants 2016 A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction Ecology and Evolution of Communication in Social Insects 2015 Cyclic Regulation of Sensory Perception by a Female Hormone Alters Behavior Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition A Molecular Code for Identity in the Vomeronasal System 2014 Murine pheromone proteins constitute a context-dependent combinatorial code governing multiple social behaviors "Sex-specific aging in flies, worms, and missing great-granddads" 2013 A bidirectional circuit switch reroutes pheromone signals in male and female brains A super-assembly of Whi3 encodes memory of deceptive encounters by single cells during yeast courtship 2012 Contact chemoreceptors mediate male-male repulsion and male-female attraction during Drosophila courtship CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression 2010 The chemical MUPpeteer The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs 2008 Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein LUSH shapes up for a starring role in olfaction 2007 Comprehensive maps of Drosophila higher olfactory centers: spatially segregated fruit and pheromone representation A map of olfactory representation in the Drosophila mushroom body A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway Tuning bulk electrostatics to regulate protein function 2006 Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes Heterotrimeric G protein signaling: Getting inside the cell Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome 2005 Feedback loops link odor and pheromone signaling with reproduction A nose by any other name (should smell as sweetly) fruitless splicing specifies male courtship behavior in Drosophila Neural circuitry that governs Drosophila male courtship behavior Olfactory inputs to hypothalamic neurons controlling reproduction and fertility 2004 Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast 2003 Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules 2002 "Pheromones, vomeronasal function, and gender-specific behavior" 2000 The molecular architecture of odor and pheromone sensing in mammals 1999 A map of pheromone receptor activation in the mammalian brain Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system 1998 Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway 1997 A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation A multigene family encoding a diverse array of putative pheromone receptors in mammals Impaired maternal behavior in mice lacking norepinephrine and epinephrine tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell 1996 Mother and daughter are doing fine: asymmetric cell division in yeast A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae A 700 bp cis-acting region controls mating-type dependent recombination along the entire left arm of yeast chromosome III Origins of cell polarity Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis 1995 A novel family of genes encoding putative pheromone receptors in mammals Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast MAP kinase pathways in yeast: for mating and more Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans 1994 Biochemical and genetic characterization of a competence pheromone from B. subtilis 1993 Bacterial sex pheromone-induced plasmid transfer How and why bacteria talk to each other FAR1 links the signal transduction pathway to the cell cycle machinery in yeast Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres 1992 The a mating type locus of U. maydis specifies cell signaling components Endocytosis in yeast: evidence for the involvement of a small GTP-binding protein (Ypt7p) A position effect on the time of replication origin activation in yeast Yeast pheromone receptor endocytosis and hyperphosphorylation are independent of G protein-mediated signal transduction 1991 Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions Pheromone-induced phosphorylation of a G protein beta subunit in S. cerevisiae is associated with an adaptive response to mating pheromone A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle SGV1 encodes a CDC28/cdc2-related kinase required for a G alpha subunit-mediated adaptive response to pheromone in S. cerevisiae S. cerevisiae alpha pheromone receptors activate a novel signal transduction pathway for mating partner discrimination 1990 "Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2" FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation Courtship in S. cerevisiae: both cell types choose mating partners by responding to the strongest pheromone signal The ERD2 gene determines the specificity of the luminal ER protein retention system FAR-reaching discoveries about the regulation of START DNA binding-induced conformational change of the yeast transcriptional activator PRTF "G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase" 1989 Constitutive mutants in the yeast pheromone response: ordered function of the gene products Epigenetic inheritance of transcriptional states in S. cerevisiae A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein 1988 a1 protein alters the DNA binding specificity of alpha 2 repressor A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain The C-terminus of the S. cerevisiae alpha-pheromone receptor mediates an adaptive response to pheromone The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain Reconstitution of SEC gene product-dependent intercompartmental protein transport 1987 "MAT alpha 1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes" Conservation of a receptor/signal transduction system "Dual regulation of the yeast CDC28-p40 protein kinase complex: cell cycle, pheromone, and nutrient limitation effects" "GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction" The yeast SCG1 gene: a G alpha-like protein implicated in the a- and alpha-factor response pathway Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and alpha-factor precursor processing A yeast operator overlaps an upstream activation site 1986 In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor Down regulation of the alpha-factor pheromone receptor in S. cerevisiae "Yeast peptide pheromones, a-factor and alpha-factor, activate a common response mechanism in their target cells" Two yeast mutants defective in endocytosis are defective in pheromone response "RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor" Secretion in yeast: reconstitution of the translocation and glycosylation of alpha-factor and invertase in a homologous cell-free system 1985 DNA topoisomerase II is required at the time of mitosis in yeast The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways The yeast STE12 product is required for expression of two sets of cell-type specific genes 1984 Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor Transcription and regulatory signals at the mating type locus in yeast 1983 Binding of alpha-factor pheromone to yeast a cells: chemical and genetic evidence for an alpha-factor receptor Control of yeast cell type by the mating type locus: positive regulation of the alpha-specific STE3 gene by the MAT alpha 1 product Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase 1982 An essential role for cyclic AMP in growth control: the case for yeast Structure of a yeast pheromone gene (MF alpha): a putative alpha-factor precursor contains four tandem copies of mature alpha-factor 1981 Cell-cycle regulation of yeast histone mRNA 1979 Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeast Recovery of S. cerevisiae a cells from G1 arrest by alpha factor pheromone requires endopeptidase action Replication of each copy of the yeast 2 micron DNA plasmid occurs during the S phase
