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Mol Biol Cell
2022
Mechanism of commitment to a mating partner in Saccharomyces cerevisiae
2021
Exploratory polarization facilitates mating partner selection in Saccharomyces cerevisiae
Bistability in the polarity circuit of yeast
Mechanisms that ensure monogamous mating in Saccharomyces cerevisiae
2019
Cell fusion in yeast is negatively regulated by components of the cell wall integrity pathway
The adaptor protein Ste50 directly modulates yeast MAPK signaling specificity through differential connections of its RA domain
MAPK modulation of yeast pheromone signaling output and the role of phosphorylation sites in the scaffold protein Ste5
2018
Mating in wild yeast: delayed interest in sex after spore germination
Analysis of the thresholds for transcriptional activation by the yeast MAP kinases Fus3 and Kss1
Tracking yeast pheromone receptor Ste2 endocytosis using fluorogen-activating protein tagging
2017
"Calcineurin, the Ca(2+)-dependent phosphatase, regulates Rga2, a Cdc42 GTPase-activating protein, to modulate pheromone signaling"
Sexual pheromone modulates the frequency of cytosolic Ca(2+) bursts in Saccharomyces cerevisiae
2015
Modulation of receptor dynamics by the regulator of G protein signaling Sst2
Pheromone-induced morphogenesis and gradient tracking are dependent on the MAPK Fus3 binding to Galpha
Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway
Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK
2013
Functional overlap among distinct G1/S inhibitory pathways allows robust G1 arrest by yeast mating pheromones
Yeast G-proteins mediate directional sensing and polarization behaviors in response to changes in pheromone gradient direction
Structurally unique interaction of RBD-like and PH domains is crucial for yeast pheromone signaling
2012
Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity
Cdc42p and Fus2p act together late in yeast cell fusion
2011
Defining pheromone-receptor signaling in Candida albicans and related asexual Candida species
2010
The beta subunit of the heterotrimeric G protein triggers the Kluyveromyces lactis pheromone response pathway in the absence of the gamma subunit
Polarization of the yeast pheromone receptor requires its internalization but not actin-dependent secretion
2009
Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway
The mating-specific Galpha interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeast
Transcriptional analysis of the Candida albicans cell cycle
Prm3p is a pheromone-induced peripheral nuclear envelope protein required for yeast nuclear fusion
Requirements for recruitment of a G protein-coupled receptor to clathrin-coated pits in budding yeast
2008
Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice
Distinct roles for two Galpha-Gbeta interfaces in cell polarity control by a yeast heterotrimeric G protein
Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase
"The same receptor, G protein, and mitogen-activated protein kinase pathway activate different downstream regulators in the alternative white and opaque pheromone responses of Candida albicans"
2007
G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans
Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans
The plasma membrane proteins Prm1 and Fig1 ascertain fidelity of membrane fusion during yeast mating
2006
Cdc42p GDP/GTP cycling is necessary for efficient cell fusion during yeast mating
Characterization of the yeast amphiphysins Rvs161p and Rvs167p reveals roles for the Rvs heterodimer in vivo
The F-box protein Dia2 regulates DNA replication
Multiple signaling pathways regulate yeast cell death during the response to mating pheromones
Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe
2005
Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast
Microtubules are dispensable for the initial pathogenic development but required for long-distance hyphal growth in the corn smut fungus Ustilago maydis
"Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males"
Golgi-to-late endosome trafficking of the yeast pheromone processing enzyme Ste13p is regulated by a phosphorylation site in its cytosolic domain
The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking
2004
Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum
Sti1 and Cdc37 can stabilize Hsp90 in chaperone complexes with a protein kinase
PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans
Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins
Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner
"The Sec1/Munc18 protein, Vps33p, functions at the endosome and the vacuole of Saccharomyces cerevisiae"
2003
The adhesin Hwp1 and the first daughter cell localize to the a/a portion of the conjugation bridge during Candida albicans mating
Regulation of the yeast amphiphysin homologue Rvs167p by phosphorylation
RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis
2002
Multiple functions of sterols in yeast endocytosis
"Pag1p, a novel protein associated with protein kinase Cbk1p, is required for cell morphogenesis and proliferation in Saccharomyces cerevisiae"
2001
Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis
O-mannosylation protects mutant alpha-factor precursor from endoplasmic reticulum-associated degradation
GGAs: roles of the different domains and comparison with AP-1 and clathrin
The Sda1 protein is required for passage through start
2000
The Kar3p kinesin-related protein forms a novel heterodimeric structure with its associated protein Cik1p
Kinetic analysis of a molecular model of the budding yeast cell cycle
Characterization of alcohol-induced filamentous growth in Saccharomyces cerevisiae
An endosome-to-plasma membrane pathway involved in trafficking of a mutant plasma membrane ATPase in yeast
Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae
The autocrine mitogenic loop of the ciliate Euplotes raikovi: the pheromone membrane-bound forms are the cell binding sites and potential signaling receptors of soluble pheromones
Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein
Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis
Organization of the yeast Golgi complex into at least four functionally distinct compartments
Yeast exocytic v-SNAREs confer endocytosis
VPS21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment
A pcl-like cyclin activates the Res2p-Cdc10p cell cycle 'start' transcriptional factor complex in fission yeast
1999
Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity
A modulatory role for clathrin light chain phosphorylation in Golgi membrane protein localization during vegetative growth and during the mating response of Saccharomyces cerevisiae
Multiple sex pheromones and receptors of a mushroom-producing fungus elicit mating in yeast
Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae
Adaptor complex-independent clathrin function in yeast
The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex
Visualization of receptor-mediated endocytosis in yeast
Specific sterols required for the internalization step of endocytosis in yeast
Structural and functional analysis of a novel coiled-coil protein involved in Ypt6 GTPase-regulated protein transport in yeast
1998
Hsp90 is required for pheromone signaling in yeast
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors
Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast
Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae
A yeast t-SNARE involved in endocytosis
1997
A novel a-factor-related peptide of Saccharomyces cerevisiae that exits the cell by a Ste6p-independent mechanism
Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans
"Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis"
The ankyrin repeat-containing protein Akr1p is required for the endocytosis of yeast pheromone receptors
An essential role of the yeast pheromone-induced Ca2+ signal is to activate calcineurin
Evidence that mating by the Saccharomyces cerevisiae gpa1Val50 mutant occurs through the default mating pathway and a suggestion of a role for ubiquitin-mediated proteolysis
Transport through the yeast endocytic pathway occurs through morphologically distinct compartments and requires an active secretory pathway and Sec18p/N-ethylmaleimide-sensitive fusion protein
The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae
1996
Identification of a ligand-binding site in an immunoglobulin fold domain of the Saccharomyces cerevisiae adhesion protein alpha-agglutinin
1995
A mating type-linked mutation that disrupts the uniparental inheritance of chloroplast DNA also disrupts cell-size control in Chlamydomonas
"end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae"
"A late Golgi sorting function for Saccharomyces cerevisiae Apm1p, but not for Apm2p, a second yeast clathrin AP medium chain-related protein"
Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway
"Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway"
1994
"Metabolic instability and constitutive endocytosis of STE6, the a-factor transporter of Saccharomyces cerevisiae"
Cell polarization directed by extracellular cues in yeast
A nuclear protein with sequence similarity to proteins implicated in human acute leukemias is important for cellular morphogenesis and actin cytoskeletal function in Saccharomyces cerevisiae
"A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog"
1993
FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1
Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms
Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast
1992
Actin- and tubulin-dependent functions during Saccharomyces cerevisiae mating projection formation
Phosphorylation of FAR1 in response to alpha-factor: a possible requirement for cell-cycle arrest
"The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution"
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024
The Pherobase
- Extensive Database of Pheromones and Semiochemicals.
Ashraf M. El-Sayed
.
Page created on 25-12-2024