| Title: | "The effect of the juvenile hormone analog, fenoxycarb on the PBAN-receptor and pheromone production in adults of the moth Helicoverpa armigera: an 'aging' hormone in adult females?" |
| Address: | "Institute for Technology & Storage of Agricultural Products, ARO, Volcani Center, Bet Dagan, Israel. vtada@volcani.agri.gov.il" |
| DOI: | 10.1016/j.jinsphys.2005.01.004 |
| ISSN/ISBN: | 0022-1910 (Print) 0022-1910 (Linking) |
| Abstract: | "In a previous study we showed that juvenile hormone (JH) or its analog, fenoxycarb (FX), is involved in the up-regulation of pheromone biosynthesis-activating neuropeptide (PBAN) competence. JH causes induction of binding to a putative PBAN-receptor (PBAN-R) and the subsequent pheromone production by pheromone glands of pharate females. The present study demonstrates that pheromone production by the adult female is age-dependent. The pheromonotropic response increased to reach a maximum at 4 days, after which a decreased response was observed. Binding of the PBAN-R was also age-dependent. Treatment with FX inhibited both binding of PBAN to the PBAN-R and the pheromonotropic response as reflected by the production of the main pheromone component, Z-11-hexadecenal. Thus, in contrast to its up-regulatory role in pharate females, FX treatment of adult females causes down-regulation of both pheromone production and specific binding to the PBAN-R. In addition, behavioural observations showed that calling behaviour, mating success and subsequent egg-fertility are affected by treating females with FX" |
| Keywords: | "Aging/physiology Animals Female Fertility Insecticides/pharmacology Juvenile Hormones/*physiology Moths/*drug effects/*physiology Neuropeptides/*metabolism Oviposition Phenylcarbamates/*pharmacology Receptors, Neuropeptide/metabolism Sex Attractants/*bios;" |
| Notes: | "MedlineRafaeli, A Bober, R eng Research Support, Non-U.S. Gov't England 2005/05/14 J Insect Physiol. 2005 Apr; 51(4):401-10. doi: 10.1016/j.jinsphys.2005.01.004" |
