| Title: | "Insect olfaction: receptors, signal transduction, and behavior" |
| Address: | "Department of Integrated Biosciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8562, Japan" |
| Journal Title: | Results Probl Cell Differ |
| ISSN/ISBN: | 0080-1844 (Print) 0080-1844 (Linking) |
| Abstract: | "The insect olfactory system is a suitable model for exploring molecular function of odorant receptors, axonal projection of olfactory receptor neurons onto secondary neurons, and the neural circuit for odor perception. Recent progress in the study of insect olfaction revealed that the heteromeric insect olfactory receptor complex forms a cation nonselective ion channel directly gated by odor or pheromone ligands independent of known G-protein signaling pathways. Despite fundamental differences in transduction machineries between insects and vertebrates, the anatomical and functional features of insect odor-coding strategy are similar and thus justify any consideration of mammalian olfaction in the study of insects. The understanding of the molecular mechanism of insect olfaction will help in the development of insect repellents for controlling insect pest and vector populations for a wide range of pathogens" |
| Keywords: | "Animals Behavior, Animal/physiology Gene Expression Profiling Insecta/genetics/*physiology Models, Biological Olfactory Pathways/physiology Receptors, Odorant/genetics/*physiology Signal Transduction/genetics/*physiology Smell/genetics/*physiology;" |
| Notes: | "MedlineSato, K Touhara, K eng Review Germany 2008/12/17 Results Probl Cell Differ. 2009; 47:121-38. doi: 10.1007/400_2008_10" |
