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J Physiol Biochem

Title:		Detection of conspecific pheromones elicits fos expression in GABA and calcium-binding cells of the rat vomeronasal system-medial extended amygdala
Author(s):		Pereno GL; Balaszczuk V; Beltramino CA;
Address:		"Catedra de Neurofisiologia y Psicofisiologia, Facultad de Psicologia, Universidad Nacional de Cordoba, Enfermera Gordillo esquina Enrique Barros, Ciudad Universitaria, 5000 Cordoba, Argentina. gpereno@psyche.unc.edu.ar"
Journal Title:		J Physiol Biochem
Year:		2011
Volume:		20101012
Issue:		1
Page Number:		71 - 85
DOI:		10.1007/s13105-010-0051-5
ISSN/ISBN:		1877-8755 (Electronic) 1138-7548 (Linking)
Abstract:		"The olfactory accessory system is specialized in the detection of pheromones, being an afferent to medial extended amygdala. In spite of the fact that numerous phenotypes are found in these structures, in the current literature, there are no detailed descriptions about the phenotype of neurons in the vomeronasal system-medial extended amygdala after their activation by pheromonal stimuli. Using immunohistochemistry for fos and dual immunohistochemistry for fos and phenotypes, here we show that females have a greater number of activated neurons by the pheromonal stimulus. Likewise, a great colocalization of fos with GABA, calretinin, and calbindin was observed in the vomeronasal system-medial extended amygdala. These data suggest that in amygdaloid areas, neuronal excitability is controlled by GABAergic neurons that contain different calcium-binding proteins, indicating the important role of inhibitory control on the incoming sensory pheromonal and olfactory inputs controlled and processed by the vomeronasal system"
Keywords:		Amygdala/anatomy & histology/cytology/*metabolism Animals Calbindin 2 Calbindins Female Immunohistochemistry/methods Male Neurons/cytology/*metabolism Olfactory Bulb/drug effects/metabolism Pheromones/*metabolism/pharmacology Proto-Oncogene Proteins c-fos;
Notes:		"MedlinePereno, German Leandro Balaszczuk, Veronica Beltramino, Carlos A eng Research Support, Non-U.S. Gov't Spain 2010/10/13 J Physiol Biochem. 2011 Mar; 67(1):71-85. doi: 10.1007/s13105-010-0051-5. Epub 2010 Oct 12"