| Title: | CMOS-MEMS VOC sensors functionalized via inkjet polymer deposition for high-sensitivity acetone detection |
| Author(s): | Perello-Roig R; Verd J; Bota S; Soberats B; Costa A; Segura J; |
| Address: | "Electronic Systems Group (GSE-UIB), University of the Balearic Islands, 07122, Palma, Spain. jaume.verd@uib.es" |
| ISSN/ISBN: | 1473-0189 (Electronic) 1473-0189 (Linking) |
| Abstract: | "CMOS-MEMS microresonators have become excellent candidates for developing portable chemical VOC sensing systems thanks to their extremely large mass sensitivity, extraordinary miniaturization capabilities, and on-chip integration with CMOS circuitry to operate as a self-sustained oscillator. This paper presents two 4-anchored MEMS plate resonators, with a resonance frequency of 2.2 MHz and 380 kHz, fabricated together with the required circuitry using a commercial 0.35 mum CMOS technology and then coated with poly-4-vinylheduorocumyl alcohol (P4V) via inkjet deposition. Such P4V constitutes a functionalization layer for specific acetone detection as a key step in the development of an integrated device for non-invasive diabetes diagnosis through exhaled human breath. The coated sensor system has been proven to increase the acetone injection response by 6-times compared to the uncoated platform and shows a cross-sensitivity to butane of 1 : 11. Experimental data show an acetone sensitivity of -0.012 ppm Hz(-1) in the best case that, together with a measured frequency Allan deviation of 0.32 ppm, provides an expected limit of detection as low as 20 ppb of acetone. Additionally, this work presents an alternative resonator design with folded flexure anchors that provide a drastic reduction of the sensor temperature sensitivity and mitigate the impact of a fluid flow inherent to the calibration system" |
| Keywords: | Acetone Exhalation Humans *Micro-Electrical-Mechanical Systems Polymers *Volatile Organic Compounds; |
| Notes: | "MedlinePerello-Roig, Rafel Verd, Jaume Bota, Sebastia Soberats, Bartomeu Costa, Antonio Segura, Jaume eng Research Support, Non-U.S. Gov't England 2021/07/22 Lab Chip. 2021 Sep 7; 21(17):3307-3315. doi: 10.1039/d1lc00484k. Epub 2021 Jul 20" |
