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Alcohol Clin Exp Res

Title:		"Effects of postnatal exposure to alcohol on reproductive physiology and sexually dimorphic behavior in a marsupial, the gray short-tailed opossum (Monodelphis domestica)"
Author(s):		Fadem BH;
Address:		"Department of Psychiatry, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark 07730"
Journal Title:		Alcohol Clin Exp Res
Year:		1993
Volume:		17
Issue:		4
Page Number:		870 - 876
DOI:		10.1111/j.1530-0277.1993.tb00856.x
ISSN/ISBN:		0145-6008 (Print) 0145-6008 (Linking)
Abstract:		"The effects of postnatal exposure to alcohol on reproductive physiology and sexually dimorphic behavior and anatomy in adult male and female gray short-tailed opossums were examined. Female responsiveness to male pheromones and fertility in both sexes were essentially normal in postnatally alcohol-treated animals. However, aspects of sexually dimorphic behavior were masculinized and defeminized in females and demasculinized in males following gonadectomy in adulthood and treatment with male (testosterone) or female (estradiol) hormones. The possible role of alterations in neural aromatase activity by perinatal alcohol exposure in mediating these behavioral effects and the potential use of this marsupial species in perinatal alcohol studies are discussed"
Keywords:		"Alcoholism/*physiopathology Animals Animals, Newborn Estradiol/physiology Estrus/drug effects/physiology Ethanol/toxicity Female Gonadal Steroid Hormones/*physiology Male Opossums Scent Glands/drug effects/physiopathology Sex Attractants/physiology Sexual;"
Notes:		"MedlineFadem, B H eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 1993/08/01 Alcohol Clin Exp Res. 1993 Aug; 17(4):870-6. doi: 10.1111/j.1530-0277.1993.tb00856.x"