| Title: | Hand-portable gas chromatograph-toroidal ion trap mass spectrometer (GC-TMS) for detection of hazardous compounds |
| Author(s): | Contreras JA; Murray JA; Tolley SE; Oliphant JL; Tolley HD; Lammert SA; Lee ED; Later DW; Lee ML; |
| Address: | "Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602-5700, USA" |
| DOI: | 10.1016/j.jasms.2008.06.022 |
| ISSN/ISBN: | 1044-0305 (Print) 1044-0305 (Linking) |
| Abstract: | "A novel gas chromatograph-mass spectrometer (GC-MS) based on a miniature toroidal ion trap mass analyzer (TMS) and a low thermal mass GC is described. The TMS system has an effective mass/charge (m/z) range of 50-442 with mass resolution at full-width half-maximum (FWHM) of 0.55 at m/z 91 and 0.80 at m/z 222. A solid-phase microextraction (SPME) fiber mounted in a simple syringe-style holder is used for sample collection and introduction into a specially designed low thermal mass GC injection port. This portable GC-TMS system weighs <13 kg (28 lb), including batteries and helium carrier gas cartridge, and is totally self-contained within dimensions of 47 x 36 x 18 cm (18.5 x 14 x 7 in.). System start-up takes about 3 min and sample analysis with library matching typically takes about 5 min, including time for column cool-down. Peak power consumption during sample analysis is about 80 W. Battery power and helium supply cartridges allow 50 and 100 consecutive analyses, respectively. Both can be easily replaced. An on-board library of target analytes is used to provide detection and identification of chemical compounds based on their characteristic retention times and mass spectra. The GC-TMS can detect 200 pg of methyl salicylate on-column. n-Butylbenzene and naphthalene can be detected at a concentration of 100 ppt in water from solid-phase microextraction (SPME) analysis of the headspace. The GC-TMS system has been designed to easily make measurements in a variety of complex and harsh environments" |
| Keywords: | "Calibration Chemical Warfare Agents/analysis Electric Power Supplies Gas Chromatography-Mass Spectrometry/*instrumentation/*methods Hazardous Substances/*analysis Hydrocarbons, Halogenated/analysis Organophosphorus Compounds/analysis Reproducibility of Re;" |
| Notes: | "MedlineContreras, Jesse A Murray, Jacolin A Tolley, Samuel E Oliphant, Joseph L Tolley, H Dennis Lammert, Stephen A Lee, Edgar D Later, Douglas W Lee, Milton L eng Research Support, U.S. Gov't, Non-P.H.S. 2008/08/02 J Am Soc Mass Spectrom. 2008 Oct; 19(10):1425-34. doi: 10.1016/j.jasms.2008.06.022. Epub 2008 Jul 3" |
