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Am J Dent

Title:		Dental calculus composition following use of essential-oil/ZnCl2 mouthrinse
Author(s):		LeGeros RZ; Rohanizadeh R; Lin S; Mijares D; LeGeros JP; Charles CH; Pan PC;
Address:		"Calcium Phosphate Research Laboratory, Department of Biomaterials and Biomimetics, New York University College of Dentistry, 345 East 24th Street, New York, NY 10010, USA. rzl1@nyu.edu"
Journal Title:		Am J Dent
Year:		2003
Volume:		16
Issue:		3
Page Number:		155 - 160
DOI:
ISSN/ISBN:		0894-8275 (Print) 0894-8275 (Linking)
Abstract:		"PURPOSE: To test the hypothesis that anticalculus agents cannot completely inhibit calculus formation but can influence the types of calcium phosphate which form, i.e., they can influence the composition of the inorganic component of human dental calculus (HDC). MATERIALS AND METHODS: The composition of HDC specimens obtained from a 16-week multi-center clinical study using three regimens were analyzed, investigators blinded. The treatment regimens were: (a) standard dentifrice (SD), (b) pyrophosphate antitartar dentifrice, and (c) SD with Tartar Control Listerine Antiseptic mouthrinse (containing essential oils and 0.09% zinc chloride). 25 individual samples and eight pooled samples from each group were analyzed using X-ray diffraction, infrared spectroscopy, and scanning electron microscopy. RESULTS: (1) relative frequency of occurrence for: (a) bacteria: Group A = 100%, Group B = 60%, and Group C = 25%; (b) Carbonate hydroxyapatite (CHA): Groups A, B, and C = 100%; (c) dicalcium phosphate dihydrate (DCPD): Group A = 55%; Group B = 45%; Group C = 80%; (2) The relative amount of DCPD is inversely proportional to that of CHA in HDC: the higher the amount of DCPD, the lower the amount of CHA. Group C regimen with essential oil/ZnCl2 mouthrinse and standard dentifrice showed a significant anti-microbial effect and favored the formation of DCPD, the most soluble Ca-P"
Keywords:		"Anti-Infective Agents, Local/therapeutic use Bacteria/ultrastructure Calcium Phosphates/analysis/classification Chlorides/*therapeutic use Dental Calculus/*chemistry Dentifrices/therapeutic use Diphosphates/therapeutic use Double-Blind Method Durapatite/a;"
Notes:		"MedlineLeGeros, Raquel Z Rohanizadeh, Ramin Lin, Shujie Mijares, Dindo LeGeros, John P Charles, Christine H Pan, Pauline C eng Clinical Trial Multicenter Study Research Support, Non-U.S. Gov't 2003/09/12 Am J Dent. 2003 Jun; 16(3):155-60"