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PLoS One

Title:		Earwax metabolomics: An innovative pilot metabolic profiling study for assessing metabolic changes in ewes during periparturition period
Author(s):		Shokry E; Pereira J; Marques Junior JG; da Cunha PHJ; Noronha Filho ADF; da Silva JA; Fioravanti MCS; de Oliveira AE; Antoniosi Filho NR;
Address:		"Laboratorio de Metodos de Extracao e Separacao (LAMES), Instituto de Quimica (IQ), Universidade Federal de Goias (UFG), Campus Samambaia, Goiania, Goias, Brazil. Escola de Veterinaria e Zootecnia, Universidade Federal de Goias (UFG), Campus Samambaia, Goiania, Goias, Brazil. Instituto de Quimica (IQ), Universidade Federal de Goias (UFG), Campus Samambaia, Goiania, Goias, Brazil"
Journal Title:		PLoS One
Year:		2017
Volume:		20170825
Issue:		8
Page Number:		e0183538 -
DOI:		10.1371/journal.pone.0183538
ISSN/ISBN:		1932-6203 (Electronic) 1932-6203 (Linking)
Abstract:		"Important metabolic changes occur during transition period of late pregnancy and early lactation to meet increasing energy demands of the growing fetus and for milk production. The aim of this investigation is to present an innovative and non-invasive tool using ewe earwax sample analysis to assess the metabolic profile in ewes during late pregnancy and early lactation. In this work, earwax samples were collected from 28 healthy Brazilian Santa Ines ewes divided into 3 sub-groups: 9 non-pregnant ewes, 6 pregnant ewes in the last 30 days of gestation, and 13 lactating ewes
Keywords:		Animals Cerumen/*metabolism Female *Metabolomics Multivariate Analysis *Parturition Pregnancy Sheep/*metabolism/physiology Volatile Organic Compounds/metabolism;
Notes:		"MedlineShokry, Engy Pereira, Juliao Marques Junior, Jair Gonzalez da Cunha, Paulo Henrique Jorge Noronha Filho, Antonio Dionisio Feitosa da Silva, Jessica Alves Fioravanti, Maria Clorinda Soares de Oliveira, Anselmo Elcana Antoniosi Filho, Nelson Roberto eng 2017/08/26 PLoS One. 2017 Aug 25; 12(8):e0183538. doi: 10.1371/journal.pone.0183538. eCollection 2017"