| Title: | Scalable Arrays of Chemical Vapor Sensors Based on DNA-Decorated Graphene |
| Address: | "Department of Mechanical and Industrial Engineering, University of Massachusetts Amherst, Amherst, MA, USA. Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, USA. cjohnson@physics.upenn.edu" |
| DOI: | 10.1007/978-1-4939-9616-2_13 |
| ISSN/ISBN: | 1940-6029 (Electronic) 1064-3745 (Linking) |
| Abstract: | "Arrays of DNA-functionalized graphene field-effect transistors (gFETs) hold great promise for high-performance vapor sensing. In this chapter, we describe methods for the scalable production of gFET-based vapor sensors with high sensitivity and efficiency in size, cost, and time. Large-area graphene sheets were prepared via chemical vapor deposition (CVD); a standard photolithographic processing for large-area graphene was used to fabricate gFETs with high mobility and low doping level under ambient conditions. The gFETs were functionalized by single-stranded DNA (ssDNA), which binds to the graphene channels through pi-pi stacking interaction and provides affinity to a wide range of chemical vapors. The resulting sensing arrays demonstrate detection of target vapor molecules down to parts-per-million concentrations with high selectivity among analytes with high chemical similarity including a series of carboxylic acids and structural isomers of carboxylic acids and pinene" |
| Keywords: | "Base Sequence Biosensing Techniques/*instrumentation/methods DNA, Single-Stranded/*chemistry/genetics Graphite/*chemistry Limit of Detection Reproducibility of Results Transistors, Electronic Volatile Organic Compounds/*analysis/chemistry DNA Field-effect;" |
| Notes: | "MedlinePing, Jinglei Johnson, A T Charlie eng Research Support, U.S. Gov't, Non-P.H.S. 2019/07/17 Methods Mol Biol. 2019; 2027:163-170. doi: 10.1007/978-1-4939-9616-2_13" |
