| Title: | Quantitative assessments of indoor air pollution and the risk of childhood acute leukemia in Shanghai |
| Author(s): | Gao Y; Zhang Y; Kamijima M; Sakai K; Khalequzzaman M; Nakajima T; Shi R; Wang X; Chen D; Ji X; Han K; Tian Y; |
| Address: | "Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University, 280 South Chongqing Road, Shanghai 200025, China. Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya 466-8550, Japan. Department of Environmental Health, Nagoya City Public Health Research Institute, Nagoya 467-8615, Japan. Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan. Department of Biostatistics, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University, 280 South Chongqing Road, Shanghai 200025, China; MOE and Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. Electronic address: tianmiejp@sjtu.edu.cn" |
| DOI: | 10.1016/j.envpol.2013.12.029 |
| ISSN/ISBN: | 1873-6424 (Electronic) 0269-7491 (Linking) |
| Abstract: | "We investigated the association between indoor air pollutants and childhood acute leukemia (AL). A total of 105 newly diagnosed cases and 105 1:1 gender-, age-, and hospital-matched controls were included. Measurements of indoor pollutants (including nitrogen dioxide (NO2) and 17 types of volatile organic compounds (VOCs)) were taken with diffusive samplers for 64 pairs of cases and controls. Higher concentrations of NO2 and almost half of VOCs were observed in the cases than in the controls and were associated with the increased risk of childhood AL. The use of synthetic materials for wall decoration and furniture in bedroom was related to the risk of childhood AL. Renovating the house in the last 5 years, changing furniture in the last 5 years, closing the doors and windows overnight in the winter and/or summer, paternal smoking history and outdoor pollutants affected VOC concentrations. Our results support the association between childhood AL and indoor air pollution" |
| Keywords: | "Acute Disease/epidemiology Air Pollutants/*analysis Air Pollution, Indoor/*analysis/statistics & numerical data Child Child, Preschool China/epidemiology Environmental Exposure/*analysis/statistics & numerical data Environmental Monitoring/methods Female;" |
| Notes: | "MedlineGao, Yu Zhang, Yan Kamijima, Michihiro Sakai, Kiyoshi Khalequzzaman, Md Nakajima, Tamie Shi, Rong Wang, Xiaojin Chen, Didi Ji, Xiaofan Han, Kaiyi Tian, Ying eng Research Support, Non-U.S. Gov't England 2014/01/28 Environ Pollut. 2014 Apr; 187:81-9. doi: 10.1016/j.envpol.2013.12.029. Epub 2014 Jan 22" |
