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Plasmid

Title:		Sex pheromones and plasmid transfer in Enterococcus faecalis
Author(s):		Clewell DB; Weaver KE;
Address:		"Department of Biologic/Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor 48109"
Journal Title:		Plasmid
Year:		1989
Volume:		21
Issue:		3
Page Number:		175 - 184
DOI:		10.1016/0147-619x(89)90041-3
ISSN/ISBN:		0147-619X (Print) 0147-619X (Linking)
Abstract:		"Plasmid-free Enterococcus faecalis excrete peptides (sex pheromones) which specifically induce a mating response in strains harboring certain conjugative plasmids. The response is characterized by the synthesis of a 'fuzzy' surface material, visible by electron microscopy, which is believed to facilitate the aggregation of donors and recipients. Transconjugants which receive a specific plasmid shut down the production of endogenous pheromone; however, they continue to produce pheromones specific for donors harboring different classes of plasmids. In this review, we summarize what is known about the biochemistry and genetics of this phenomenon. Some emphasis is given to the hemolysin plasmid pAD1 and the regulation of its conjugal transfer"
Keywords:		"Amino Acid Sequence *Conjugation, Genetic DNA Transposable Elements Enterococcus faecalis/*genetics Hemolysin Factors Membrane Proteins/genetics Molecular Sequence Data Pheromones/*genetics *Plasmids Restriction Mapping Sex Attractants/*genetics/physiolog;"
Notes:		"MedlineClewell, D B Weaver, K E eng AI10318/AI/NIAID NIH HHS/ DE02731/DE/NIDCR NIH HHS/ GM33956/GM/NIGMS NIH HHS/ Research Support, U.S. Gov't, P.H.S. Review 1989/05/01 Plasmid. 1989 May; 21(3):175-84. doi: 10.1016/0147-619x(89)90041-3"