Bedoukian   RussellIPM   RussellIPM   Piezoelectric Micro-Sprayer


Home
Animal Taxa
Plant Taxa
Semiochemicals
Floral Compounds
Semiochemical Detail
Semiochemicals & Taxa
Synthesis
Control
Invasive spp.
References

Abstract

Guide

Alphascents
Pherobio
InsectScience
E-Econex
Counterpart-Semiochemicals
Print
Email to a Friend
Kindly Donate for The Pherobase

« Previous AbstractDevelopmental programming: Preconceptional and gestational exposure of sheep to a real-life environmental chemical mixture alters maternal metabolome in a fetal sex-specific manner    Next Abstract"Floral morphology and anatomy of Ophiocaryon, a paedomorphic genus of Sabiaceae" »

J Antibiot (Tokyo)


Title:Discovering potential Streptomyces hormone producers by using disruptants of essential biosynthetic genes as indicator strains
Author(s):Thao NB; Kitani S; Nitta H; Tomioka T; Nihira T;
Address:"International Center for Biotechnology, Osaka University, Osaka, Japan. Faculty of Science, MU-OU Collaborative Research Center for Bioscience and Biotechnology, Mahidol University, Bangkok, Thailand"
Journal Title:J Antibiot (Tokyo)
Year:2017
Volume:20170719
Issue:10
Page Number:1004 - 1008
DOI: 10.1038/ja.2017.85
ISSN/ISBN:1881-1469 (Electronic) 0021-8820 (Linking)
Abstract:"Autoregulators are low-molecular-weight signaling compounds that control the production of many secondary metabolites in actinomycetes and have been referred to as 'Streptomyces hormones'. Here, potential producers of Streptomyces hormones were investigated in 40 Streptomyces and 11 endophytic actinomycetes. Production of gamma-butyrolactone-type (IM-2, VB) and butenolide-type (avenolide) Streptomyces hormones was screened using Streptomyces lavendulae FRI-5 (DeltafarX), Streptomyces virginiae (DeltabarX) and Streptomyces avermitilis (Deltaaco), respectively. In these strains, essential biosynthetic genes for Streptomyces hormones were disrupted, enabling them to respond solely to the externally added hormones. The results showed that 20% of each of the investigated strains produced IM-2 and VB, confirming that gamma-butyrolactone-type Streptomyces hormones are the most common in actinomycetes. Unlike the gamma-butyrolactone type, butenolide-type Streptomyces hormones have been discovered in recent years, but their distribution has been unclear. Our finding that 24% of actinomycetes (12 of 51 strains) showed avenolide activity revealed for the first time that the butenolide-type Streptomyces hormone is also common in actinomycetes"
Keywords:*Gene Knockout Techniques Mass Screening Metabolic Networks and Pathways/*genetics Microbiological Techniques Pheromones/chemistry/classification/*metabolism Streptomyces/*metabolism;
Notes:"MedlineThao, Nguyen B Kitani, Shigeru Nitta, Hiroko Tomioka, Toshiya Nihira, Takuya eng England 2017/09/28 J Antibiot (Tokyo). 2017 Oct; 70(10):1004-1008. doi: 10.1038/ja.2017.85. Epub 2017 Jul 19"

 
Back to top
 
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024 The Pherobase - Extensive Database of Pheromones and Semiochemicals. Ashraf M. El-Sayed.
Page created on 19-12-2024