| Title: | Breath Sensor Technology for the Use in Mechanical Lung Ventilation Equipment for Monitoring Critically Ill Patients |
| Author(s): | Bhandari MP; Veliks V; Stonans I; Padilla M; Suba O; Svare A; Krupnova I; Ivanovs N; Bema D; Mitrovics J; Leja M; |
| Address: | "Institute of Clinical and Preventive Medicine, University of Latvia, LV-1586 Riga, Latvia. JLM Innovation GmbH, D-72070 Tubingen, Germany. Riga East University Hospital, LV-1038 Riga, Latvia. Faculty of Medicine, University of Latvia, LV-1586 Riga, Latvia" |
| DOI: | 10.3390/diagnostics12020430 |
| ISSN/ISBN: | 2075-4418 (Print) 2075-4418 (Electronic) 2075-4418 (Linking) |
| Abstract: | "BACKGROUND: The need for mechanical lung ventilation is common in critically ill patients, either with COVID-19 infection or due to other causes. Monitoring of patients being ventilated is essential for timely and improved management. We here propose the use of a novel breath volatile organic compound sensor technology to be used in a mechanical lung ventilation machine for this purpose; the technology was evaluated in critically ill COVID-19 patients on mechanical lung ventilation. METHODS: Based on the consistency results of our study data, the breath sensor device with metal oxide gas sensors and environment-controlling sensors was mounted on the ventilation exhaust port of the ventilation machine; this allowed to ensure additional safety since the device was placed outside the contour between the patient and equipment. RESULTS: The sensors allowed stable registration of the signals for up to several weeks for 10 patients in total, depending on the storage amount; a proportion of patients were intubated or received tracheostoma during the evaluation period. Future studies are on the way to correlate sensor readings to other parameters characterizing the severity of the patient condition and outcome. CONCLUSIONS: We suppose that such technology will allow patient monitoring in real-time for timely identification of deterioration, potentially requiring some change of management. The obtained results are preliminary and further studies are needed to examine their clinical significance" |
| Keywords: | Covid-19 VOC sensors exhaled breath mechanical ventilation patient monitoring; |
| Notes: | "PubMed-not-MEDLINEBhandari, Manohar Prasad Veliks, Viktors Stonans, Ilmars Padilla, Marta Suba, Olegs Svare, Agija Krupnova, Inga Ivanovs, Nikita Bema, Dina Mitrovics, Jan Leja, Marcis eng VPP-COVID-2020/1-0023/Ministry of Education and Science/ Switzerland 2022/02/26 Diagnostics (Basel). 2022 Feb 7; 12(2):430. doi: 10.3390/diagnostics12020430" |
