| Title: | Curcuma ecalcarata - new natural source of pinocembrin and piperitenone |
| Author(s): | Rameshkumar KB; Alan Sheeja DB; Nair MS; George V; |
| Address: | "a Phytochemistry and Phytopharmacology Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Palode, Thiruvananthapuram 695 562 , Kerala , India" |
| DOI: | 10.1080/14786419.2014.994210 |
| ISSN/ISBN: | 1478-6427 (Electronic) 1478-6419 (Linking) |
| Abstract: | "Phytochemical analysis of the rhizome extract of Curcuma ecalcarata, a hitherto uninvestigated south Western Ghats endemic species, resulted in the isolation and identification of the diaryl heptanoid trans, trans-1,7-diphenyl-5-hydroxy-4,6-heptadiene-3-one (1), steroid beta-sitosterol (2), flavanone pinocembrin (4) and monoterpenoids piperitenone (3) and 8-hydroxy piperitone (5). HPTLC estimation of pinocembrin in the rhizome revealed the plant as a rich source of pinocembrin (0.37% dry wt.). The rhizome essential oil was isolated by hydrodistillation and analysed by GC-FID, GC-MS and (13)C NMR. Among the 30 constituents identified in the oil, monoterpenoids predominated (94.2%) followed by sesquiterpenoids (5.8%). The major compound consisting of 65.2% of the oil was isolated and identified as piperitenone (3). The study highlights the plant as a rich source of the flavanone pinocembrin and the volatile aroma compound piperitenone" |
| Keywords: | "Curcuma/*chemistry Cyclohexane Monoterpenes Flavanones/*chemistry Gas Chromatography-Mass Spectrometry Magnetic Resonance Spectroscopy Molecular Structure Monoterpenes/*chemistry Oils, Volatile/chemistry Plant Extracts/*chemistry Plant Oils/chemistry Rhiz;" |
| Notes: | "MedlineRameshkumar, K B Alan Sheeja, D B Nair, Mangalam S George, V eng Research Support, Non-U.S. Gov't England 2015/01/03 Nat Prod Res. 2015; 29(13):1276-9. doi: 10.1080/14786419.2014.994210. Epub 2015 Jan 2" |
