| Title: | Exposure to volatile organic compounds in healthcare settings |
| Author(s): | LeBouf RF; Virji MA; Saito R; Henneberger PK; Simcox N; Stefaniak AB; |
| Address: | "National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA. Center for Indoor Environments and Health, University of Connecticut Health Center, Farmington, Connecticut, USA" |
| DOI: | 10.1136/oemed-2014-102080 |
| ISSN/ISBN: | 1470-7926 (Electronic) 1351-0711 (Print) 1351-0711 (Linking) |
| Abstract: | "OBJECTIVES: To identify and summarise volatile organic compound (VOC) exposure profiles of healthcare occupations. METHODS: Personal (n=143) and mobile area (n=207) evacuated canisters were collected and analysed by a gas chromatograph/mass spectrometer to assess exposures to 14 VOCs among 14 healthcare occupations in five hospitals. Participants were volunteers identified by their supervisors. Summary statistics were calculated by occupation. Principal component analysis (PCA) was used to reduce the 14 analyte inputs to five orthogonal factors and identify occupations that were associated with these factors. Linear regressions were used to assess the association between personal and mobile area samples. RESULTS: Exposure profiles differed among occupations; ethanol had the highest geometric mean (GM) among nursing assistants ( approximately 4900 and approximately 1900 microg/m(3), personal and area), and 2-propanol had the highest GM among medical equipment preparers ( approximately 4600 and approximately 2000 microg/m(3), personal and area). The highest total personal VOC exposures were among nursing assistants ( approximately 9200 microg/m(3)), licensed practical nurses ( approximately 8700 microg/m(3)) and medical equipment preparers ( approximately 7900 microg/m(3)). The influence of the PCA factors developed from personal exposure estimates varied by occupation, which enabled a comparative assessment of occupations. For example, factor 1, indicative of solvent use, was positively correlated with clinical laboratory and floor stripping/waxing occupations and tasks. Overall, a significant correlation was observed (r=0.88) between matched personal and mobile area samples, but varied considerably by analyte (r=0.23-0.64). CONCLUSIONS: Healthcare workers are exposed to a variety of chemicals that vary with the activities and products used during activities. These VOC profiles are useful for estimating exposures for occupational hazard ranking for industrial hygienists as well as epidemiological studies" |
| Keywords: | "Air Pollutants, Occupational/*analysis/toxicity Environmental Monitoring/methods Health Personnel *Hospitals, Veterans Humans Occupational Exposure/adverse effects/*analysis Principal Component Analysis Regression Analysis United States Volatile Organic C;" |
| Notes: | "MedlineLeBouf, Ryan F Virji, M Abbas Saito, Rena Henneberger, Paul K Simcox, Nancy Stefaniak, Aleksandr B eng CC999999/Intramural CDC HHS/ England 2014/07/12 Occup Environ Med. 2014 Sep; 71(9):642-50. doi: 10.1136/oemed-2014-102080. Epub 2014 Jul 10" |
