2022

Quorum Sensing Regulation of a Major Facilitator Superfamily Transporter Affects Multiple Streptococcal Virulence Factors

"The Outer Surface Protease, SepM, Is Required for blp Locus Activation in Three of the Four Most Common Pherotypes of Streptococcus pneumoniae"

The Proteomic and Transcriptomic Landscapes Altered by Rgg2/3 Activity in Streptococcus pyogenes

"Structural Differences in Complexes between the Master Regulator PrgX, Peptide Pheromones, and Operator Binding Sites Determine the Induction State for Conjugative Transfer of pCF10"

2021

Let Me Upgrade You: Impact of Mobile Genetic Elements on Enterococcal Adaptation and Evolution

2020

Involvement of Chromosomally Encoded Homologs of the RRNPP Protein Family in Enterococcus faecalis Biofilm Formation and Urinary Tract Infection Pathogenesis

Roles of the Site 2 Protease Eep in Staphylococcus aureus

Single-Cell Analysis Reveals that the Enterococcal Sex Pheromone Response Results in Expression of Full-Length Conjugation Operon Transcripts in All Induced Cells

2018

Mechanistic Features of the Enterococcal pCF10 Sex Pheromone Response and the Biology of Enterococcus faecalis in Its Natural Habitat

Identification of Streptococcus gallolyticus subsp. gallolyticus (Biotype I) Competence-Stimulating Peptide Pheromone

Planktonic Interference and Biofilm Alliance between Aggregation Substance and Endocarditis- and Biofilm-Associated Pili in Enterococcus faecalis

A Quorum Sensing-Regulated Protein Binds Cell Wall Components and Enhances Lysozyme Resistance in Streptococcus pyogenes

2017

Examination of Enterococcus faecalis Toxin-Antitoxin System Toxin Fst Function Utilizing a Pheromone-Inducible Expression Vector with Tight Repression and Broad Dynamic Range

2016

"Enterococcal Sex Pheromones: Evolutionary Pathways to Complex, Two-Signal Systems"

2015

The fsr Quorum-Sensing System and Cognate Gelatinase Orchestrate the Expression and Processing of Proprotein EF_1097 into the Mature Antimicrobial Peptide Enterocin O16

Antisocial luxO Mutants Provide a Stationary-Phase Survival Advantage in Vibrio fischeri ES114

The formation of Streptococcus mutans persisters induced by the quorum-sensing peptide pheromone is affected by the LexA regulator

An electrostatic interaction between BlpC and BlpH dictates pheromone specificity in the control of bacteriocin production and immunity in Streptococcus pneumoniae

Regulation of Bioluminescence in Photobacterium leiognathi Strain KNH6

A Social Medium: ASM's 5th Cell-Cell Communication in Bacteria Meeting in Review

2014

Competence for genetic transformation in Streptococcus pneumoniae: mutations in sigmaA bypass the comW requirement

"PrgK, a multidomain peptidoglycan hydrolase, is essential for conjugative transfer of the pheromone-responsive plasmid pCF10"

2013

Cell death of Streptococcus mutans induced by a quorum-sensing peptide occurs via a conserved streptococcal autolysin

The HtrA protease of Streptococcus pneumoniae controls density-dependent stimulation of the bacteriocin blp locus via disruption of pheromone secretion

Cyclic AMP receptor protein regulates pheromone-mediated bioluminescence at multiple levels in Vibrio fischeri ES114

Competence for natural genetic transformation in the Streptococcus bovis group streptococci S. infantarius and S. macedonicus

Substrate specificity and function of the pheromone receptor AinR in Vibrio fischeri ES114

Redundant group a streptococcus signaling peptides exhibit unique activation potentials

2012

In vivo and in vitro analyses of regulation of the pheromone-responsive prgQ promoter by the PrgX pheromone receptor protein

Development of competence for genetic transformation of Streptococcus mutans in a chemically defined medium

"Draft genome sequence of the volatile organic compound-producing Antarctic bacterium Arthrobacter sp. strain TB23, able to inhibit cystic fibrosis pathogens belonging to the Burkholderia cepacia complex"

Extracellular identification of a processed type II ComR/ComS pheromone of Streptococcus mutans

The cryptic competence pathway in Streptococcus pyogenes is controlled by a peptide pheromone

A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance

2011

Enterococcus faecalis virulence regulator FsrA binding to target promoters

Purification and characterization of dimethylsulfide monooxygenase from Hyphomicrobium sulfonivorans

Regulation of the competence pathway as a novel role associated with a streptococcal bacteriocin

Quorum sensing contributes to natural transformation of Vibrio cholerae in a species-specific manner

2010

A novel pheromone quorum-sensing system controls the development of natural competence in Streptococcus thermophilus and Streptococcus salivarius

Direct evidence for control of the pheromone-inducible prgQ operon of Enterococcus faecalis plasmid pCF10 by a countertranscript-driven attenuation mechanism

Bright mutants of Vibrio fischeri ES114 reveal conditions and regulators that control bioluminescence and expression of the lux operon

"A genetic determinant in Streptococcus gordonii Challis encodes a peptide with activity similar to that of enterococcal sex pheromone cAM373, which facilitates intergeneric DNA transfer"

2009

Bacteriocin activity of Streptococcus pneumoniae is controlled by the serine protease HtrA via posttranscriptional regulation

Competence for genetic transformation in Streptococcus pneumoniae: termination of activity of the alternative sigma factor ComX is independent of proteolysis of ComX and ComW

Structure-activity relationship of gelatinase biosynthesis-activating pheromone of Enterococcus faecalis

The StkP/PhpP signaling couple in Streptococcus pneumoniae: cellular organization and physiological characterization

"Plasmid pAMS1-encoded, bacteriocin-related 'Siblicide' in Enterococcus faecalis"

2008

Characterization of the sequence specificity determinants required for processing and control of sex pheromone by the intramembrane protease Eep and the plasmid-encoded protein PrgY

"Enterococcus faecalis PcfC, a spatially localized substrate receptor for type IV secretion of the pCF10 transfer intermediate"

Lipoprotein signal peptides are processed by Lsp and Eep of Streptococcus uberis

"CSF, a species-specific extracellular signaling peptide for communication among strains of Bacillus subtilis and Bacillus mojavensis"

Cloning and genetic analyses of the bacteriocin 41 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pYI14: a novel bacteriocin complemented by two extracellular components (lysin and activator)

"Genetic analysis of the Enterococcus vancomycin resistance conjugative plasmid pHTbeta: identification of the region involved in cell aggregation and traB, a key regulator gene for plasmid transfer and cell aggregation"

2007

Analysis of the amino acid sequence specificity determinants of the enterococcal cCF10 sex pheromone in interactions with the pheromone-sensing machinery

Characterization of an active partition system for the Enterococcus faecalis pheromone-responding plasmid pAD1

Control of the transcription of a short gene encoding a cyclic peptide in Streptococcus thermophilus: a new quorum-sensing system?

Quorum-sensing regulation of the production of Blp bacteriocins in Streptococcus thermophilus

Siamycin attenuates fsr quorum sensing mediated by a gelatinase biosynthesis-activating pheromone in Enterococcus faecalis

Structure-activity analysis of quorum-sensing signaling peptides from Streptococcus mutans

2006

"A hydrophobic patch in the competence-stimulating Peptide, a pneumococcal competence pheromone, is essential for specificity and biological activity"

Positive selection in the ComC-ComD system of Streptococcal Species

Revised model for Enterococcus faecalis fsr quorum-sensing system: the small open reading frame fsrD encodes the gelatinase biosynthesis-activating pheromone propeptide corresponding to staphylococcal agrd

2005

Characterization of the pheromone response of the Enterococcus faecalis conjugative plasmid pCF10: complete sequence and comparative analysis of the transcriptional and phenotypic responses of pCF10-containing cells to pheromone induction

Genetic analysis of transfer-related regions of the vancomycin resistance Enterococcus conjugative plasmid pHTbeta: identification of oriT and a putative relaxase gene

"Synthesis of autoinducer 2 by the lyme disease spirochete, Borrelia burgdorferi"

Specific control of endogenous cCF10 pheromone by a conserved domain of the pCF10-encoded regulatory protein PrgY in Enterococcus faecalis

Regulation of bacteriocin production in Streptococcus mutans by the quorum-sensing system required for development of genetic competence

2004

Diversifying selection at the Bacillus quorum-sensing locus and determinants of modification specificity during synthesis of the ComX pheromone

Replication of Enterococcus faecalis pheromone-responding plasmid pAD1: location of the minimal replicon and oriV site and RepA involvement in initiation of replication

Two separate quorum-sensing systems upregulate transcription of the same ABC transporter in Streptococcus pneumoniae

2003

Competence-induced cells of Streptococcus pneumoniae lyse competence-deficient cells of the same strain during cocultivation

"Structural analysis of the peptide pheromone receptor PlnB, a histidine protein kinase from Lactobacillus plantarum"

"Transient association of an alternative sigma factor, ComX, with RNA polymerase during the period of competence for genetic transformation in Streptococcus pneumoniae"

The Streptococcus pneumoniae cia regulon: CiaR target sites and transcription profile analysis

"Role of the Enterococcus faecalis GelE protease in determination of cellular chain length, supernatant pheromone levels, and degradation of fibrin and misfolded surface proteins"

2002

Identification of the cAD1 sex pheromone precursor in Enterococcus faecalis

"ccfA, the genetic determinant for the cCF10 peptide pheromone in Enterococcus faecalis OG1RF"

"Characterization of comQ and comX, two genes required for production of ComX pheromone in Bacillus subtilis"

"Functional analysis of TraA, the sex pheromone receptor encoded by pPD1, in a promoter region essential for the mating response in Enterococcus faecalis"

Analysis of the conjugal transfer system of the pheromone-independent highly transferable Enterococcus plasmid pMG1: identification of a tra gene (traA) up-regulated during conjugation

Competence without a competence pheromone in a natural isolate of Streptococcus infantis

2001

DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli

Natural genetic transformation of Streptococcus mutans growing in biofilms

The KlGpa1 gene encodes a G-protein alpha subunit that is a positive control element in the mating pathway of the budding yeast Kluyveromyces lactis

Analysis of functional domains of the Enterococcus faecalis pheromone-induced surface protein aggregation substance

"Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules"

Specificity and genetic polymorphism of the Bacillus competence quorum-sensing system

2000

Cell-associated pheromone peptide (cCF10) production and pheromone inhibition in Enterococcus faecalis

Heterologous inducible expression of Enterococcus faecalis pCF10 aggregation substance asc10 in Lactococcus lactis and Streptococcus gordonii contributes to cell hydrophobicity and adhesion to fibrin

Mapping of the Cryptococcus neoformans MATalpha locus: presence of mating type-specific mitogen-activated protein kinase cascade homologs

"Pheromone-regulated expression of sex pheromone plasmid pAD1-encoded aggregation substance depends on at least six upstream genes and a cis-acting, orientation-dependent factor"

"A pAD1-encoded small RNA molecule, mD, negatively regulates Enterococcus faecalis pheromone response by enhancing transcription termination"

1999

Identification and characterization of a determinant (eep) on the Enterococcus faecalis chromosome that is involved in production of the peptide sex pheromone cAD1

Horizontal transfer of genetic material among Saccharomyces yeasts

Acetone formation in the Vibrio family: a new pathway for bacterial leucine catabolism

"Mutational analysis and membrane topology of ComP, a quorum-sensing histidine kinase of Bacillus subtilis controlling competence development"

Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway

Swarming by Pseudomonas syringae B728a requires gacS (lemA) and gacA but not the acyl-homoserine lactone biosynthetic gene ahlI

1998

Altered srf expression in Bacillus subtilis resulting from changes in culture pH is dependent on the Spo0K oligopeptide permease and the ComQX system of extracellular control

Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa

Efficient transfer of the pheromone-independent Enterococcus faecium plasmid pMG1 (Gmr) (65.1 kilobases) to Enterococcus strains during broth mating

Molecular mechanism of peptide-specific pheromone signaling in Enterococcus faecalis: functions of pheromone receptor TraA and pheromone-binding protein TraC encoded by plasmid pPD1

luxI- and luxR-homologous genes of Rhizobium etli CNPAF512 contribute to synthesis of autoinducer molecules and nodulation of Phaseolus vulgaris

Analogs of the autoinducer 3-oxooctanoyl-homoserine lactone strongly inhibit activity of the TraR protein of Agrobacterium tumefaciens

"Salmonella typhimurium encodes an SdiA homolog, a putative quorum sensor of the LuxR family, that regulates genes on the virulence plasmid"

1997

Natural competence in the genus Streptococcus: evidence that streptococci can change pherotype by interspecies recombinational exchanges

Cloning and genetic analysis of the UV resistance determinant (uvr) encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pAD1

Cloning and genetic and sequence analyses of the bacteriocin 21 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pPD1

"Regulation of transfer of the Enterococcus faecalis pheromone-responding plasmid pAD1: temperature-sensitive transfer mutants and identification of a new regulatory determinant, traD"

pigB determines a diffusible factor needed for extracellular polysaccharide slime and xanthomonadin production in Xanthomonas campestris pv. campestris

A quorum-sensing system in the free-living photosynthetic bacterium Rhodobacter sphaeroides

1996

Mutations within the first LSGGQ motif of Ste6p cause defects in a-factor transport and mating in Saccharomyces cerevisiae

Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone

Cloning and genetic organization of the bacteriocin 31 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pYI17

"The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment"

1995

Genetic analysis of a region of the Enterococcus faecalis plasmid pCF10 involved in positive regulation of conjugative transfer functions

"Cloning and characterization of a region of Enterococcus faecalis plasmid pPD1 encoding pheromone inhibitor (ipd), pheromone sensitivity (traC), and pheromone shutdown (traB) genes"

Transcriptional analysis of a region of the Enterococcus faecalis plasmid pCF10 involved in positive regulation of conjugative transfer functions

Pheromone-inducible conjugation in Enterococcus faecalis: interbacterial and host-parasite chemical communication

Physical mapping of the conjugative bacteriocin plasmid pPD1 of Enterococcus faecalis and identification of the determinant related to the pheromone response

Phase variation of Enterococcus faecalis pAD1 conjugation functions relates to changes in iteron sequence region

Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genes

1994

A lipoprotein signal peptide encoded by the staphylococcal conjugative plasmid pSK41 exhibits an activity resembling that of Enterococcus faecalis pheromone cAD1

A LuxR-LuxI type regulatory system activates Agrobacterium Ti plasmid conjugal transfer in the presence of a plant tumor metabolite

Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants

"The prgQ gene of the Enterococcus faecalis tetracycline resistance plasmid pCF10 encodes a peptide inhibitor, iCF10"

1993

"Cloning and molecular analysis of genes affecting expression of binding substance, the recipient-encoded receptor(s) mediating mating aggregate formation in Enterococcus faecalis"

High-resolution visualization by field emission scanning electron microscopy of Enterococcus faecalis surface proteins encoded by the pheromone-inducible conjugative plasmid pCF10

The cell-bound fructosyltransferase of Streptococcus salivarius: the carboxyl terminus specifies attachment in a Streptococcus gordonii model system

"Cloning and characterization of a region of the Enterococcus faecalis conjugative plasmid, pCF10, encoding a sex pheromone-binding function"

Characterization of the traC determinant of the Enterococcus faecalis hemolysin-bacteriocin plasmid pAD1: binding of sex pheromone

"Identification, characterization, and nucleotide sequence of a region of Enterococcus faecalis pheromone-responsive plasmid pAD1 capable of autonomous replication"

Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: expression of the positive regulator TraE1

1992

Evidence that the hemolysin/bacteriocin phenotype of Enterococcus faecalis subsp. zymogenes can be determined by plasmids in different incompatibility groups as well as by the chromosome

Conjugative transfer of Enterococcus faecalis plasmid pAD1: nucleotide sequence and transcriptional fusion analysis of a region involved in positive regulation

Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: nucleotide sequence analysis of traA

1991

Glycosylation and structure of the yeast MF alpha 1 alpha-factor precursor is important for efficient transport through the secretory pathway

Comparative analysis of Enterococcus faecalis sex pheromone plasmids identifies a single homologous DNA region which codes for aggregation substance

Molecular and genetic analysis of a region of plasmid pCF10 containing positive control genes and structural genes encoding surface proteins involved in pheromone-inducible conjugation in Enterococcus faecalis

Role of the pheromone-inducible surface protein Asc10 in mating aggregate formation and conjugal transfer of the Enterococcus faecalis plasmid pCF10

1990

"CsgA, an extracellular protein essential for Myxococcus xanthus development"

Thermotolerance is independent of induction of the full spectrum of heat shock proteins and of cell cycle blockage in the yeast Saccharomyces cerevisiae

"Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: effects of host strain and traA, traB, and C region mutants on expression of an E region pheromone-inducible lacZ fusion"

1989

Isolation of a sexual sporulation hormone from Aspergillus nidulans

N alpha acetylation is required for normal growth and mating of Saccharomyces cerevisiae

Saccharomyces cerevisiae protein kinase dependent on Ca2+ and calmodulin

1988

Cloning and expression of genes encoding pheromone-inducible antigens of Enterococcus (Streptococcus) faecalis

Dynamic aspects of vacuolar and cytosolic amino acid pools of Saccharomyces cerevisiae

Effect of calcofluor white on chitin synthases from Saccharomyces cerevisiae

Isolation and characterization of Saccharomyces cerevisiae mutants resistant to Calcofluor white

Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: construction and characterization of lacZ transcriptional fusions in a key control region of the plasmid

1987

"Isolation and structure of the sex pheromone inhibitor, iPD1, excreted by Streptococcus faecalis donor strains harboring plasmid pPD1"

Identification of the structural gene for dipeptidyl aminopeptidase yscV (DAP2) of Saccharomyces cerevisiae

Two conjugation systems associated with Streptococcus faecalis plasmid pCF10: identification of a conjugative transposon that transfers between S. faecalis and Bacillus subtilis

Transfer functions of the Streptococcus faecalis plasmid pAD1: organization of plasmid DNA encoding response to sex pheromone

Transfer of the conjugal tetracycline resistance transposon Tn916 from Streptococcus faecalis to Staphylococcus aureus and identification of some insertion sites in the staphylococcal chromosome

Purification and characterization of a Ca2+-dependent membrane peptidase involved in the signaling of mating pheromone in Rhodosporidium toruloides

Pheromone induction of agglutination in Saccharomyces cerevisiae a cells

1986

Identification of pheromone-induced surface proteins in Streptococcus faecalis and evidence of a role for lipoteichoic acid in formation of mating aggregates

Analysis of developmentally defective chemical signaling mutants of Polysphondylium violaceum

Agglutination and mating activity of the MF alpha 2-encoded alpha-factor analog in Saccharomyces cerevisiae

"Biological activity of the Asn-5,Arg-7 tridecapeptide encoded by MF alpha 2 of Saccharomyces cerevisiae"

"Mediation, by Saccharomyces cerevisiae translocation signals, of beta-lactamase transport through the Escherichia coli inner membrane and sensitive method for detection of signal sequences"

1985

Alpha mating type-specific expression of mutations leading to constitutive agglutinability in Saccharomyces cerevisiae

"Involvement of protein sulfhydryls in the trigger reaction of rhodotorucine A, a farnesyl peptide mating pheromone of Rhodosporidium toruloides"

Identification of multiple cell surface antigens associated with the sex pheromone response of Streptococcus faecalis

Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918)

Transient increase of Ca2+ uptake as a signal for mating pheromone-induced differentiation in the heterobasidiomycetous yeast Rhodosporidium toruloides

1984

Different structure-function relationships for alpha-factor-induced morphogenesis and agglutination in Saccharomyces cerevisiae

"Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen"

Mating pheromone-induced alteration of cell surface proteins in the heterobasidiomycetous yeast Tremella mesenterica

1983

Extracellular suppression allows mating by pheromone-deficient sterile mutants of Saccharomyces cerevisiae

Identification and partial characterization of a pheromone-induced adhesive surface antigen of Streptococcus faecalis

Expression of the BAR1 gene in Saccharomyces cerevisiae: induction by the alpha mating pheromone of an activity associated with a secreted protein

Podospora mutant defective in glucose-dependent growth control

1982

Genetic and physiological analysis of conjugation in Streptococcus faecalis

Trail following by gliding bacteria

Role of metabolism of the mating pheromone in sexual differentiation of the heterobasidiomycete Rhodosporidium toruloides

Pheromone produced by the myxobacterium Stigmatella aurantiaca

1981

"Adenosine 3',5'-phosphate phosphodiesterase and pheromone response in the yeast Saccharomyces cerevisiae"

Sexual agglutination in Saccharomyces cerevisiae

1980

Altered immunochemical reactivity of Saccharomyces cerevisiae a-cells after alpha-factor-induced morphogenesis

Sex pheromone cAD1 in Streptococcus faecalis: induction of a function related to plasmid transfer

1979

Evidence for a hierarchical mating system operating via pheromones in Dictyostelium giganteum

Mating pheromones of Saccharomyces kluyveri: pheromone interactions between Saccharomyces kluyveri and Saccharomyces cerevisiae

1978

Cell-cell recognition in Saccharomyces cerevisiae: regulation of mating-specific adhesion

Control of vacuole permeability and protein degradation by the cell cycle arrest signal in Saccharomyces cerevisiae

Reaction order of Saccharomyces cerevisiae alpha-factor-mediated cell cycle arrest and mating inhibition

1977

Recovery of Saccharomyces cerevisiae mating-type a cells from G1 arrest by alpha factor

1976

Morphogenic effects of alpha-factor on Saccharomyces cerevisiae a cells

1962

Some nutritional characteristics of predominant culturable ruminal bacteria