2020

Ligand- and pH-Induced Structural Transition of Gypsy Moth Lymantria dispar Pheromone-Binding Protein 1 (LdisPBP1)

2019

Design of a De Novo Aggregating Antimicrobial Peptide and a Bacterial Conjugation-Based Delivery System

Pheromone Perception: Mechanism of the Reversible Coil-Helix Transition in Antheraea polyphemus Pheromone-Binding Protein 1

2013

Structural insights into the ligand binding and releasing mechanism of Antheraea polyphemus pheromone-binding protein 1: role of the C-terminal tail

2010

Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor

NMR structure of navel orangeworm moth pheromone-binding protein (AtraPBP1): implications for pH-sensitive pheromone detection

Binding conformation and kinetics of two pheromone-binding proteins from the Gypsy moth Lymantria dispar with biological and nonbiological ligands

2009

Identification of specific transmembrane residues and ligand-induced interface changes involved in homo-dimer formation of a yeast G protein-coupled receptor

Structural basis of the broad specificity of a general odorant-binding protein from honeybee

Structure and function of Vps15 in the endosomal G protein signaling pathway

Identification of amino acids at two dimer interface regions of the alpha-factor receptor (Ste2)

2008

Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment

Structural characterization of sulfated steroids that activate mouse pheromone-sensing neurons

2007

Double-mutant cycle scanning of the interaction of a peptide ligand and its G protein-coupled receptor

2006

Secretory proteins as potential semiochemical carriers in the horse

Solution structure of a chemosensory protein from the desert locust Schistocerca gregaria

Accessibility of cysteine residues substituted into the cytoplasmic regions of the alpha-factor receptor identifies the intracellular residues that are available for G protein interaction

2005

Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor

Biosynthesis and NMR analysis of a 73-residue domain of a Saccharomyces cerevisiae G protein-coupled receptor

Comparison of class A and D G protein-coupled receptors: common features in structure and activation

"Purification and characterization of a recombinant G-protein-coupled receptor, Saccharomyces cerevisiae Ste2p, transiently expressed in HEK293 EBNA1 cells"

Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity

2004

A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast

Identification of ligand binding regions of the Saccharomyces cerevisiae alpha-factor pheromone receptor by photoaffinity cross-linking

2003

Sequences in the intracellular loops of the yeast pheromone receptor Ste2p required for G protein activation

"NMR solution structure of attractin, a water-borne protein pheromone from the mollusk Aplysia californica"

"Thermodynamic analysis of binding between mouse major urinary protein-I and the pheromone 2-sec-butyl-4,5-dihydrothiazole"

2002

"Molecular and functional characterization of an odorant binding protein of the Asian elephant, Elephas maximus: implications for the role of lipocalins in mammalian olfaction"

Direct identification of a G protein ubiquitination site by mass spectrometry

Genetic remodeling and transcriptional remodeling of subtelomeric heterochromatin are different

Tyr266 in the sixth transmembrane domain of the yeast alpha-factor receptor plays key roles in receptor activation and ligand specificity

Identification of a contact region between the tridecapeptide alpha-factor mating pheromone of Saccharomyces cerevisiae and its G protein-coupled receptor by photoaffinity labeling

2001

Probing the binding domain of the Saccharomyces cerevisiae alpha-mating factor receptor with rluorescent ligands

ATR-FTIR study of the structure and orientation of transmembrane domains of the Saccharomyces cerevisiae alpha-mating factor receptor in phospholipids

Mutational analysis of the role of N-glycosylation in alpha-factor receptor function

2000

A limited spectrum of mutations causes constitutive activation of the yeast alpha-factor receptor

Discrimination of pheromone enantiomers by two pheromone binding proteins from the gypsy moth Lymantria dispar

Synthesis and biophysical analysis of transmembrane domains of a Saccharomyces cerevisiae G protein-coupled receptor

1999

"NMR mapping of the recombinant mouse major urinary protein I binding site occupied by the pheromone 2-sec-butyl-4,5-dihydrothiazole"

Cryptoregiochemistry of the delta11-myristoyl-CoA desaturase involved in the biosynthesis of Spodoptera littoralis sex pheromone

1998

Plantaricin A is an amphiphilic alpha-helical bacteriocin-like pheromone which exerts antimicrobial and pheromone activities through different mechanisms

"Synthesis, biological activity, and conformational analysis of peptidomimetic analogues of the Saccharomyces cerevisiae alpha-factor tridecapeptide"

Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast

1997

Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1)

Novel modifications to the farnesyl moiety of the a-factor lipopeptide pheromone from Saccharomyces cerevisiae: a role for isoprene modifications in ligand presentation

Backbone structure and dynamics of a hemolymph protein from the mealworm beetle Tenebrio molitor

"Functional interactions between synthetic alkyl phospholipids and the ABC transporters P-glycoprotein, Ste-6, MRP, and Pgh 1"

1996

Partitioning of a-factor analogues into membranes: analysis of binding and importance for biological activity

Partial constitutive activation of pheromone responses by a palmitoylation-site mutant of a G protein alpha subunit in yeast

1995

Protein structure encodes the ligand binding specificity in pheromone binding proteins

Systematic analysis of the Saccharomyces cerevisiae alpha-factor containing lactam constraints of different ring size

Synthesis and biological activity of fluorescent yeast pheromones

1994

"Conformational analysis of the Saccharomyces cerevisiae tridecapeptide mating pheromone by 13C,15N rotational-echo double resonance nuclear magnetic resonance spectroscopy"

Odorant binding by a pheromone binding protein: active site mapping by photoaffinity labeling

1993

Histidine2 of the alpha-factor of Saccharomyces cerevisiae is not essential for binding to its receptor or for biological activity

Conformational analysis of [D-Ala9]alpha-factor and [L-Ala9]alpha-factor in solution and in the presence of lipid

Role of prenylation in the interaction of the a-factor mating pheromone with phospholipid bilayers

1992

Antagonistic and synergistic peptide analogues of the tridecapeptide mating pheromone of Saccharomyces cerevisiae

1989

"Purification, characterization, and amino acid sequence of the mating pheromone Er-10 of the ciliate Euplotes raikovi"

Purification and biochemical characterization of recombinant hirudin produced by Saccharomyces cerevisiae

Cultures of separated mating types of Blakeslea trispora make D and E forms of trisporic acids

Interaction of the Saccharomyces cerevisiae alpha-factor with phospholipid vesicles as revealed by proton and phosphorus NMR

1987

Synthesis and biological activity of amino terminus extended analogues of the alpha mating factor of Saccharomyces cerevisiae

1985

"Biological activity and conformational isomerism in position 9 analogues of the des-1-tryptophan,3-beta-cyclohexylalanine-alpha-factor from Saccharomyces cerevisiae"

Structure-activity relationships in the dodecapeptide alpha-factor of Saccharomyces cerevisiae: position 6 analogues are poor inducers of agglutinability

1983

Structure-activity relationships in the dodecapeptide alpha factor of Saccharomyces cerevisiae

1981

Synthesis of brominated heptanones and bromoform by a bromoperoxidase of marine origin