| Title: | [Quality evaluation of Artemisiae Argyi Folium based on fingerprint analysis and quantitative analysis of multicomponents] |
| Author(s): | Guo L; Jiao Q; Zhang D; Liu AP; Wang Q; Zheng YG; |
| Address: | "College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. Hebei Key Laboratory of Chinese Medicine Research on Cardio-cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China" |
| Journal Title: | Zhongguo Zhong Yao Za Zhi |
| DOI: | 10.19540/j.cnki.cjcmm.2018.0029 |
| ISSN/ISBN: | 1001-5302 (Print) 1001-5302 (Linking) |
| Abstract: | "Artemisiae Argyi Folium, the dried leaves of Artemisia argyi, has been widely used in traditional Chinese and folk medicines for treatment of hemorrhage, pain, and skin itch. Phytochemical studies indicated that volatile oil, organic acid and flavonoids were the main bioactive components in Artemisiae Argyi Folium. Compared to the volatile compounds, the research of nonvolatile compounds in Artemisiae Argyi Folium are limited. In the present study, an accurate and reliable fingerprint approach was developed using HPLC for quality control of Artemisiae Argyi Folium. A total of 10 common peaks were marked??eand the similarity of all the Artemisiae Argyi Folium samples was above 0.940. The established fingerprint method could be used for quality control of Artemisiae Argyi Folium. Furthermore, an HPLC method was applied for simultaneous determination of seven bioactive compounds including five organic acids and two flavonoids in Artemisiae Argyi Folium and Artemisiae Lavandulaefoliae Folium samples. Moreover, chemometrics methods such as hierarchical clustering analysis and principal component analysis were performed to compare and discriminate the Artemisiae Argyi Folium and Artemisiae Lavandulaefoliae Folium based on the quantitative data of analytes. The results indicated that simultaneous quantification of multicomponents coupled with chemometrics analysis could be a well-acceptable strategy to identify and evaluate the quality of Artemisiae Argyi Folium" |
| Keywords: | "Artemisia/*chemistry Chromatography, High Pressure Liquid Drugs, Chinese Herbal/*standards Flavonoids/*analysis Plant Leaves/*chemistry Artemisiae Argyi Folium chemometrics methods fingerprint analysis quality evaluation quantitative analysis;" |
| Notes: | "MedlineGuo, Long Jiao, Qian Zhang, Dan Liu, Ai-Peng Wang, Qian Zheng, Yu-Guang chi China 2018/04/21 Zhongguo Zhong Yao Za Zhi. 2018 Mar; 43(5):977-984. doi: 10.19540/j.cnki.cjcmm.2018.0029" |
