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Chem Biodivers

Title:		"Volatile Chemical Composition, Antibacterial and Antifungal Activities of Extracts from Different Parts of Globba schomburgkii Hook.f"
Author(s):		Doungchawee J; Kulsing C; Suekaew N; Na Pombejra S; Chavasiri W; Plabutong N; Thammahong A; Khotavivattana T;
Address:		"Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Science, Chulalongkorn University, Bangkok, 10330, Thailand. Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. Antimicrobial Resistance and Stewardship Research Unit, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand"
Journal Title:		Chem Biodivers
Year:		2019
Volume:		20190404
Issue:		5
Page Number:		e1900057 -
DOI:		10.1002/cbdv.201900057
ISSN/ISBN:		1612-1880 (Electronic) 1612-1872 (Linking)
Abstract:		"Globba schomburgkii Hook.f. is an ornamental plant that has recently found increasing demand as cut flowers, hence generating a significant number of by-products from different parts of the plant. To investigate the further applications of these by-products, twelve crude extracts from rhizomes, stalks, leaves, and flowers were prepared by serial exhaustive extraction. The volatile composition of these extracts was analyzed by GC/MS; a total of 89 compounds were identified, most of which were sesquiterpenes as well as some labdane-type diterpenes. The antimicrobial activities of these extracts were evaluated, revealing a correlation between the terpenoid content and antibacterial activities. Notably, the dichloromethane extracts of rhizomes and flowers, which contained the highest amount of terpenoids (e. g., alpha-gurjunene, guaia-9,11-diene, gamma-bicyclohomofarnesal, beta-caryophyllene, and caryophyllene oxide), displayed the most prominent antibacterial activities. This work demonstrates the potential use of the crude extracts from G. schomburgkii as natural antibacterial ingredients for pharmaceutical and other applications"
Keywords:		Anti-Bacterial Agents/*chemistry/isolation & purification/pharmacology Antifungal Agents/*chemistry/isolation & purification/pharmacology Aspergillus/drug effects Candida albicans/drug effects Flowers/chemistry/metabolism Gas Chromatography-Mass Spectrome;
Notes:		"MedlineDoungchawee, Jeerapat Kulsing, Chadin Suekaew, Naruemon Na Pombejra, Sarisa Chavasiri, Warinthorn Plabutong, Napasawan Thammahong, Arsa Khotavivattana, Tanatorn eng CU-GR_62_01_23_01/Chulalongkorn University/ Saraburi Provincial Health Office and Seeding Money for New Faculty Member/ Department of Chemistry, Chulalongkorn University/ Switzerland 2019/02/23 Chem Biodivers. 2019 May; 16(5):e1900057. doi: 10.1002/cbdv.201900057. Epub 2019 Apr 4"