| Title: | Recent chemical exposures and blood volatile organic compound levels in a large population-based sample |
| Author(s): | Churchill JE; Ashley DL; Kaye WE; |
| Address: | "Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia, USA" |
| DOI: | 10.1080/00039890109604068 |
| ISSN/ISBN: | 0003-9896 (Print) 0003-9896 (Linking) |
| Abstract: | "Little is known about factors that influence blood levels of volatile organic compounds in nonoccupationally exposed populations. The authors examined the possible relationship between recent self-reported chemical exposures and elevated blood volatile organic compound levels among 982 adult participants in theThird National Health and Nutrition Examination Survey. A strong dose-response effect was indicated (p < .001) for increasing lifetime pack-years of cigarettes smoked for elevated levels of toluene, styrene, and benzene. A positive dose-response effect was indicated for daily alcohol consumption with respect to elevated blood levels of 2-butanone and acetone. For volatile organic compounds typically found in 10-75% of the population, the establishment of a link with specific environmental exposures is relatively easy because there is less effect of confounding in this group. Some volatile organic compounds, however, are seen in less than 10% of the general population; finding these compounds at any level may warrant a search for a particular exposure" |
| Keywords: | "Adult *Environmental Exposure Ethnicity Female Humans Hydrocarbons, Chlorinated/*blood Income Logistic Models Male Middle Aged Nutrition Surveys *Population Surveillance Risk Factors Smoking/adverse effects United States Urban Population;" |
| Notes: | "MedlineChurchill, J E Ashley, D L Kaye, W E eng 2001/05/08 Arch Environ Health. 2001 Mar-Apr; 56(2):157-66. doi: 10.1080/00039890109604068" |
