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Food Res Int

Title:		"Towards a better understanding of Artemisia vulgaris: Botany, phytochemistry, pharmacological and biotechnological potential"
Author(s):		Abiri R; Silva ALM; de Mesquita LSS; de Mesquita JWC; Atabaki N; de Almeida EB; Shaharuddin NA; Malik S;
Address:		"Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia; Young Researchers and Elite Club of IAU, Kermanshah, Iran. Health Sciences Graduate Program, Biological & Health Sciences Center, Federal University of Maranhao, Sao Luis, MA, Brazil. Laboratory of Pharmacognosy, Department of Pharmacy, Federal University of Maranhao, Sao Luis, MA, Brazil. IAU of Tehran Science and Research Branch, Tehran, Iran. Health Sciences Graduate Program, Biological & Health Sciences Center, Federal University of Maranhao, Sao Luis, MA, Brazil; Laboratory of Botanical Studies, Department of Biology, Biological and Health Sciences Center, Federal University of Maranhao, Sao Luis, MA, Brazil. Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia. Health Sciences Graduate Program, Biological & Health Sciences Center, Federal University of Maranhao, Sao Luis, MA, Brazil. Electronic address: 777soniamalik@gmail.com"
Journal Title:		Food Res Int
Year:		2018
Volume:		20180329
Issue:
Page Number:		403 - 415
DOI:		10.1016/j.foodres.2018.03.072
ISSN/ISBN:		1873-7145 (Electronic) 0963-9969 (Linking)
Abstract:		"Artemisia vulgaris is one of the important medicinal plant species of the genus Artemisia, which is usually known for its volatile oils. The genus Artemisia has become the subject of great interest due to its chemical and biological diversity as well as the discovery and isolation of promising anti-malarial drug artemisinin. A. vulgaris has a long history in treatment of human ailments by medicinal plants in various parts of the world. This medicinal plant possesses a broad spectrum of therapeutic properties including: anti-malarial, anti-inflammatory, anti-hypertensive, anti-oxidant, anti-tumoral, immunomodulatory, hepatoprotective, anti-spasmodic and anti-septic. These activities are mainly attributed to the presence of various classes of secondary metabolites, including flavonoids, sesquiterpene lactones, coumarins, acetylenes, phenolic acids, organic acids, mono- and sesquiterpenes. Studies related to A. vulgaris morphology, anatomy and phytochemistry has gained a significant interest for better understanding of production and accumulation of therapeutic compounds in this species. Recently, phytochemical and pharmacological investigations have corroborated the therapeutic potential of bioactive compounds of A. vulgaris. These findings provided further evidence for gaining deeper insight into the identification and isolation of novel compounds, which act as alternative sources of anti-malarial drugs in a cost-effective manner. Considering the rising demand and various medical applications of A. vulgaris, this review highlights the recent reports on the chemistry, biological activities and biotechnological interventions for controlled and continuous production of bioactive compounds from this plant species"
Keywords:		"Animals Artemisia/*chemistry/classification/growth & development Humans Oils, Volatile/isolation & purification/*pharmacology Phytochemicals/isolation & purification/*pharmacology Phytotherapy/*methods Plant Extracts/isolation & purification/*pharmacology;"
Notes:		"MedlineAbiri, Rambod Silva, Abraao Lincoln Macedo de Mesquita, Ludmilla Santos Silva de Mesquita, Jose Wilson Carvalho Atabaki, Narges de Almeida, Eduardo Bezerra Jr Shaharuddin, Noor Azmi Malik, Sonia eng Research Support, Non-U.S. Gov't Review Canada 2018/05/29 Food Res Int. 2018 Jul; 109:403-415. doi: 10.1016/j.foodres.2018.03.072. Epub 2018 Mar 29"