| Title: | Development of solid-phase microextraction followed by gas chromatography-mass spectrometry for rapid analysis of volatile organic chemicals in mainstream cigarette smoke |
| Address: | "Department of Chemistry, Shangrao Normal University, Shangrao 334001, Province of Jiangxi, China. sryq6333@163.com" |
| DOI: | 10.1016/j.chroma.2008.10.063 |
| ISSN/ISBN: | 0021-9673 (Print) 0021-9673 (Linking) |
| Abstract: | "In this work, a novel, simple and efficient method based on solid-phase microextraction (SPME) followed by gas chromatography-mass spectrometry (GC-MS) was developed to the analysis of volatile organic chemicals (VOCs) in mainstream cigarette smoke (MCS). Using a simple home-made smoking machine device, extraction and concentration of VOCs in MCS were performed by SPME fiber, and the VOCs adsorbed on fiber were desorbed, and analyzed by GC-MS. The extraction fiber types and the desorption conditions were studied, and the method precision was also investigated. After the investigation, the optimal fiber was divinylbenzene/carboxen/polydemethylsiloxane (DVB/CAR/PDMS), and the optimal desorption condition was 250 degrees C for 3 min. The method precision was from 2% to 11%. Finally, the proposed method was tested by its application of the analysis of VOCs in MCS from 10 brands of cigarettes and one reference cigarette. A total of 70 volatile compounds were identified by the proposed method. The experimental results showed that the proposed method was a simple, rapid, reliable, and solvent-free technique for the determination of VOCs in MCS" |
| Keywords: | "Air Pollution, Indoor/analysis Gas Chromatography-Mass Spectrometry/methods Smoke/analysis Solid Phase Microextraction/methods Tobacco/*chemistry Volatile Organic Compounds/*analysis;" |
| Notes: | "MedlineYe, Qing eng Netherlands 2008/11/11 J Chromatogr A. 2008 Dec 12; 1213(2):239-44. doi: 10.1016/j.chroma.2008.10.063. Epub 2008 Oct 21" |
