| Title: | Highly Selective Volatile Organic Compounds Breath Analysis Using a Broadly-Tunable Vertical-External-Cavity Surface-Emitting Laser |
| Author(s): | Tuzson B; Jagerska J; Looser H; Graf M; Felder F; Fill M; Tappy L; Emmenegger L; |
| Address: | "Laboratory for Air Pollution and Environmental Technology, Swiss Federal Laboratories for Materials Science and Technology (Empa) , 8600 Dubendorf, Switzerland. Department of Physics and Technology, UiT-The Arctic University of Norway , 9019 Tromso, Norway. Institute for Aerosol and Sensor Technology, Fachhochschule Nordwestschweiz (FHNW) , 5210 Windisch, Switzerland. Camlin Technologies AG , 8005 Zurich, Switzerland. Faculty of Biology and Medicine, Department of Physiology, Universite de Lausanne (UNIL) , 1005 Lausanne, Switzerland" |
| DOI: | 10.1021/acs.analchem.6b04511 |
| ISSN/ISBN: | 1520-6882 (Electronic) 0003-2700 (Linking) |
| Abstract: | "A broadly tunable mid-infrared vertical-external-cavity surface-emitting laser (VECSEL) is employed in a direct absorption laser spectroscopic setup to measure breath acetone. The large wavelength coverage of more than 30 cm(-1) at 3.38 mum allows, in addition to acetone, the simultaneous measurement of isoprene, ethanol, methanol, methane, and water. Despite the severe spectral interferences from water and alcohols, an unambiguous determination of acetone is demonstrated with a precision of 13 ppbv that is achieved after 5 min averaging at typical breath mean acetone levels in synthetic gas samples mimicking human breath" |
| Keywords: | Breath Tests Humans *Lasers Surface Properties Volatile Organic Compounds/*analysis; |
| Notes: | "MedlineTuzson, Bela Jagerska, Jana Looser, Herbert Graf, Manuel Felder, Ferdinand Fill, Matthias Tappy, Luc Emmenegger, Lukas eng Research Support, Non-U.S. Gov't 2017/05/18 Anal Chem. 2017 Jun 20; 89(12):6377-6383. doi: 10.1021/acs.analchem.6b04511. Epub 2017 May 26" |
