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Chem Biodivers

Title:		Evaluation of Antibacterial Activity of Lavandulapedunculata subsp. atlantica (Braun-Blanq.) Romo Essential Oil and Selected Terpenoids against Resistant Bacteria Strains-Structure-Activity Relationships
Author(s):		Sayout A; Ouarhach A; Rabie R; Dilagui I; Soraa N; Romane A;
Address:		"Laboratory of Applied Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech, 40000, Morocco. Laboratory of Application Organic Chemistry, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, Fez B.P. 2202, Morocco. Laboratory of Microbiology and Virology, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, B.P. 7010, Morocco"
Journal Title:		Chem Biodivers
Year:		2020
Volume:		20200107
Issue:		1
Page Number:		e1900496 -
DOI:		10.1002/cbdv.201900496
ISSN/ISBN:		1612-1880 (Electronic) 1612-1872 (Linking)
Abstract:		"The genus Lavandula is known for its different uses in traditional medicine. This study is interested in the chemical composition of Lavandulapedunculata subsp.atlantica (Braun-Blanq.) Romo as well as evaluating its antibacterial potential against multi-resistant strains. The analysis of Lavandulaatlantica essential oil (LAEO) allows the identification of 47 components representing 93.6 % of all identified. The main constituent of LAEO was camphor (50.4 %), followed by fenchone (14.1 %) and camphene (5.6 %). The antibacterial assays revealed that LAEO was active against all the studied bacteria. A preliminary study of the relationship between certain terpenoids and antibacterial activity was also carried out in order to note the compound(s) that are responsible for LAEO's antibacterial activity. This study showed that the activity of the essential oil may be due to the presence of certain minor compounds such as carvone, considering the presence of the synergistic effect between the essential oil"
Keywords:		"Anti-Bacterial Agents/analysis/*pharmacology Bacteria/*drug effects Dose-Response Relationship, Drug Drug Resistance, Multiple, Bacterial/*drug effects Lavandula/*chemistry Microbial Sensitivity Tests Oils, Volatile/analysis/*pharmacology Structure-Activi;"
Notes:		"MedlineSayout, Ahlam Ouarhach, Aicha Rabie, Reda Dilagui, Ilham Soraa, Nabila Romane, Abderrahmane eng Switzerland 2020/01/08 Chem Biodivers. 2020 Jan; 17(1):e1900496. doi: 10.1002/cbdv.201900496. Epub 2020 Jan 7"