| Title: | Histamine excretion in common indoor and hematophagous arthropods |
| Author(s): | Principato S; Romero A; Lee CY; Campbell K; Choe DH; Schal C; DeVries Z; |
| Address: | "Department of Entomology, University of Kentucky, Lexington, KY, USA. Department of Entomology, Plant Pathology and Weed Science, New Mexico State University, Las Cruces, NM, USA. Department of Entomology, University of California, 900 University Avenue, Riverside, CA, USA. Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, USA" |
| ISSN/ISBN: | 1938-2928 (Electronic) 0022-2585 (Linking) |
| Abstract: | "Histamine is a biogenic amine that regulates multiple physiological functions in diverse organisms, specifically playing a central role in the mammalian immune response. The common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), excretes histamine in large amounts in its feces as a component of its aggregation pheromone, which contaminates homes. The potential health risks associated with the presence of indoor histamine are unclear, but to predict future exposure risks, it is critical that we understand if other arthropods excrete histamine in any discernible phylogenetic pattern. In the present study, we evaluated histamine excretion by various arthropods; specifically those commonly found in large numbers indoors, other hematophagous species, and other species in the order Hemiptera. To evaluate arthropods for histamine excretion, rearing containers for each arthropod were swabbed and/or the harborage substrates were collected. Samples were then analyzed for the presence of histamine using gas chromatography-mass spectrometry. For those arthropods where histamine was present above the method detection limit, total histamine excretion was quantified over a period of 2 wk. Our results indicate that histamine excretion is limited to hematophagous hemipterans (bed bugs, bat bugs, tropical bed bugs, and kissing bugs), suggesting that indoor histamine contamination in the United States can be primarily linked to bed bugs" |
| Keywords: | bed bug feces hemipteran histamine indoor environment; |
| Notes: | "PublisherPrincipato, Simona Romero, Alvaro Lee, Chow-Yang Campbell, Kathleen Choe, Dong-Hwan Schal, Coby DeVries, Zachary eng DP5-OD028155/NH/NIH HHS/ England 2023/08/24 J Med Entomol. 2023 Aug 24:tjad103. doi: 10.1093/jme/tjad103" |
