| Title: | Exposure of humans to a volatile organic mixture. I. Behavioral assessment |
| Author(s): | Otto DA; Hudnell HK; House DE; Molhave L; Counts W; |
| Address: | "Health Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina" |
| DOI: | 10.1080/00039896.1992.9935940 |
| ISSN/ISBN: | 0003-9896 (Print) 0003-9896 (Linking) |
| Abstract: | "Exposure to a low-level mixture of volatile organic compounds, typical of those found in new buildings, has been reported to impair neurobehavioral function in persons who have experienced sick building syndrome (SBS). Sixty-six healthy young males who had no history of chemical sensitivity were exposed for 2.75 h to a complex mixture of volatile organic compounds at 0 and 25 mg/m3. Even though subjects reported more fatigue and more mental confusion following exposure to volatile organic compounds than to clean air, performance on 13 neurobehavioral tests was not affected. Practice or learning effects were observed if administration of many behavioral tests were repeated. Further studies are needed to clarify the relationship of exposure to volatile organic chemicals, neurobehavioral performance, and subject characteristics, e.g., age, gender, and chemical sensitivity" |
| Keywords: | "Adolescent Adult Air Pollution, Indoor/*adverse effects Construction Materials/adverse effects Emotions/drug effects Humans Male Mental Processes/*drug effects Psychological Tests Psychomotor Performance/*drug effects Volatilization;" |
| Notes: | "MedlineOtto, D A Hudnell, H K House, D E Molhave, L Counts, W eng 1992/01/01 Arch Environ Health. 1992 Jan-Feb; 47(1):23-30. doi: 10.1080/00039896.1992.9935940" |
