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J Chromatogr A

Title:		Microfabricated ionic liquid column for separations in dry air
Author(s):		Li MW; Huang X; Zhu H; Kurabayashi K; Fan X;
Address:		"Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Center for Wireless Integrated MicroSensing and Systems (WIMS(2)), University of Michigan, Ann Arbor, MI 48109, USA; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA. Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Center for Wireless Integrated MicroSensing and Systems (WIMS(2)), University of Michigan, Ann Arbor, MI 48109, USA. Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA; Department of Mechanical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA. Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Center for Wireless Integrated MicroSensing and Systems (WIMS(2)), University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: xsfan@umich.edu"
Journal Title:		J Chromatogr A
Year:		2020
Volume:		20200227
Issue:
Page Number:		461002 -
DOI:		10.1016/j.chroma.2020.461002
ISSN/ISBN:		1873-3778 (Electronic) 0021-9673 (Linking)
Abstract:		"Micro gas chromatography (microGC) is a technique developed for rapid, in situ analysis of volatile organic compounds (VOCs) for environmental protection, industrial monitoring, and toxicology. While reduced microGC size and power requirements allow for increased portability, the low moisture and oxygen resilience of current microcolumn technology result in increased peak broadening and tailing for humid samples, which necessitates the use of bulky helium or nitrogen carrier gas cartridges. Developing a microcolumn to address these deficiencies is desirable to improve microGC field performance and further reduce microGC system size. This paper reports the development and characterization of a microfabricated phosphonium ionic liquid (microIL) column and demonstrates separation of both polar and nonpolar compounds using this column via analyses of alcohols, chloroalkanes, aromatics, aldehydes, fatty acid methyl esters, and alkanes. The microIL column achieved operation at temperatures up to 345 degrees C for fatty acid methyl ester and alkane separation. Notably, all separations in this study used dry air as the carrier gas, showing that analysis of a diverse range of compounds was possible in the presence of oxygen. After exposure to dry air for 48 h at temperatures up to 220 degrees C, the microIL column's peak capacity was only degraded by 8.92%, which validated its long-term robustness against oxygen. The column's separation performance was not degraded by high moisture concentrations or long-term moisture exposure, also manifesting its robustness to moisture. The high temperature, moisture, and oxygen resilience of the microIL column enable more rapid separations in varying field environments without requiring additional microGC accessories (e.g., humidity filters and carrier gas cartridges). The microIL column is therefore expected to be useful for integration into future microGC devices"
Keywords:		"Air Alkanes/chemistry Chromatography, Gas/*methods Fatty Acids/chemistry Hot Temperature Hydrocarbons, Aromatic/chemistry Ionic Liquids/*chemistry Microtechnology Dry air Gas chromatography Ionic liquid Microfabricated column Stationary phase;"
Notes:		"MedlineLi, Maxwell Wei-Hao Huang, Xiaolu Zhu, Hongbo Kurabayashi, Katsuo Fan, Xudong eng Netherlands 2020/03/08 J Chromatogr A. 2020 Jun 7; 1620:461002. doi: 10.1016/j.chroma.2020.461002. Epub 2020 Feb 27"