| Title: | [Determination of volatile organic compounds in blood by headspace solid-phase microextraction-gas chromatography] |
| Author(s): | Hao S; Kang J; Zhou S; Cui J; |
| Address: | "Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China" |
| ISSN/ISBN: | 1000-8020 (Print) 1000-8020 (Linking) |
| Abstract: | "The headspace solid-phase microextraction (HS-SPME) is a novel extraction technique and has been developed rapidly. It is a fast, simple, solventless and sensitive method for sampling, separating, extracting, injecting and analyzing volatile organic compounds. This paper presents the research work in detecting volatile organic compounds(including ten compounds) in blood. The extraction fiber is made by fused-silica fiber with 100 microns polydimethylsiloxane (PDMS). The extraction time of the method was 10 min. The thermal desorption time was 1 min. It was found that the optimized location of the extraction fiber in the injector of GC was to put the whole needle in the injector. The precision of the method was determined to be less 5% relative standard deviation (RSD). The linear range of the detection was rather wide. The lowest detectin limits (LODs) were all < or = 5 ng/ml" |
| Keywords: | "Animals Benzene/*analysis Benzene Derivatives/*blood Chromatography, Gas Guinea Pigs Tetrachloroethylene/*blood;" |
| Notes: | "MedlineHao, S Kang, J Zhou, S Cui, J chi English Abstract Research Support, Non-U.S. Gov't China 2003/05/03 Wei Sheng Yan Jiu. 2000 Jan 30; 29(1):37-9" |
