| Title: | Rapid Growth of Zinc Oxide Nanotube-Nanowire Hybrid Architectures and Their Use in Breast Cancer-Related Volatile Organics Detection |
| Author(s): | Katwal G; Paulose M; Rusakova IA; Martinez JE; Varghese OK; |
| Address: | "Jacobs Technology, Structural Engineering, NASA Johnson Space Center , Houston, Texas 77058, United States" |
| DOI: | 10.1021/acs.nanolett.5b05280 |
| ISSN/ISBN: | 1530-6992 (Electronic) 1530-6984 (Linking) |
| Abstract: | "A simple direct method for the rapid fabrication of zinc oxide nanotube-nanowire hybrid structure in an environmentally friendly way is described here. Zinc foils were anodized in an aqueous solution of washing soda and baking soda at room temperature in order to obtain the hybrid architecture. At the beginning of the process nanowires were formed on the substrate. The wider nanowires transformed into nanotubes in about a minute and grew in length with time. The morphological integrity was maintained upon heat treatment at temperatures up to the melting point of the substrate ( approximately 400 degrees C) except that the nanotube wall became porous. The chemiresistor devices fabricated using the heat-treated structure exhibited high response to low-concentration volatile organic compounds that are considered markers for breast cancer. The response was not significantly affected by high humidity or presence of hydrogen, methane, or carbon dioxide. The devices are expected to find use as breath sensors for noninvasive early detection of breast cancer" |
| Keywords: | "Biomarkers, Tumor/analysis Biosensing Techniques/methods Breast Neoplasms/*diagnosis Breath Tests/instrumentation Female Humans Humidity Nanotubes/*chemistry Nanowires/*chemistry Porosity Reproducibility of Results Sensitivity and Specificity Surface Prop;" |
| Notes: | "MedlineKatwal, Giwan Paulose, Maggie Rusakova, Irene A Martinez, James E Varghese, Oomman K eng Research Support, Non-U.S. Gov't 2016/04/06 Nano Lett. 2016 May 11; 16(5):3014-21. doi: 10.1021/acs.nanolett.5b05280. Epub 2016 Apr 11" |
