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Molecules

Title:		Volatile organic compounds from Centaurium erythraea Rafn (Croatia) and the antimicrobial potential of its essential oil
Author(s):		Jerkovic I; Gaso-Sokac D; Pavlovic H; Marijanovic Z; Gugic M; Petrovic I; Kovac S;
Address:		"Department of Organic Chemistry, Faculty of Chemistry & Technology, University of Split, N. Tesle 10/V, HR-21000 Split, Croatia. igor@ktf-split.hr"
Journal Title:		Molecules
Year:		2012
Volume:		20120220
Issue:		2
Page Number:		2058 - 2072
DOI:		10.3390/molecules17022058
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"GC and MS were used for the analysis of Croatian Centaurium erythraea Rafn essential oil (obtained by hydrodistillation) and headspace (applying headspace solid-phase microextraction). The headspace contained numerous monoterpene hydrocarbons (the major ones were terpinene-4-ol, methone, p-cymene, gamma-terpinene and limonene). Oxygenated monoterpenes were present in the headspace and oil, while 1,8-cineole, bornyl acetate and verbenone were present only in the headspace. High headspace percentages of toluene and naphthalene were found, followed by hemimellitene. Lot of similarities were observed with Serbian C. erythraea oil [neophytadiene (1.4%), thymol (2.6%), carvacrol (6.1%) and hexadecanoic acid (5.7%)], but different features were also noted such as the presence of menthol, menthone and phytone. The oil fractionation enabled identification of other minor compounds not found in total oil such as norisoprenoides, alk-1-enes or chromolaenin. The essential oil showed antimicrobial potential on Escherichia coli, Salmonella enteritidis, Staphylococcus aureus and Bacillus cereus. On the other hand, no antibacterial activity of the oil was observed on Pseudomonas fluorescens and Lysteria monocytogenes"
Keywords:		"Anti-Bacterial Agents/*chemistry/*pharmacology Bacteria/*drug effects Benzene Derivatives/chemistry Bicyclic Monoterpenes Camphanes/chemistry Centaurium/*chemistry Chromatography, Gas/methods Croatia Cyclohexanols/chemistry Eucalyptol Hydrocarbons/chemist;"
Notes:		"MedlineJerkovic, Igor Gaso-Sokac, Dajana Pavlovic, Hrvoje Marijanovic, Zvonimir Gugic, Mirko Petrovic, Ivana Kovac, Spomenka eng Research Support, Non-U.S. Gov't Switzerland 2012/02/22 Molecules. 2012 Feb 20; 17(2):2058-72. doi: 10.3390/molecules17022058"