| Title: | WeiTsing: a new face of Ca(2+)-permeable channels in plant immunity |
| Address: | "State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China. lijfeng3@mail.sysu.edu.cn" |
| DOI: | 10.1007/s44154-023-00110-4 |
| ISSN/ISBN: | 2731-0450 (Electronic) 2731-0450 (Linking) |
| Abstract: | "Plants employ pattern- and effector-triggered immunity (PTI and ETI) to synergistically defend invading pathogens and insect herbivores. Both PTI and ETI can induce cytosolic Ca(2+) spikes, despite in different spatiotemporal patterns, to activate downstream Ca(2+)-dependent immune signaling cascades. While multiple families of Ca(2+)-permeable channels at the plasma membrane have been uncovered, the counterparts responsible for Ca(2+) release from intracellular stores remain poorly understood. In a groundbreaking paper published recently by Cell, the authors reported that WeiTsing, an Arabidopsis endoplasmic reticulum (ER)-resident protein that was specifically expressed in the pericycle upon Plasmodiophora brassicae (Pb) infection, could form resistosome-like Ca(2+)-conducting channel and protect the stele of Brassica crops from Pb colonization. As the channel activity of WeiTsing was indispensable for its immune function, the findings highlight a previously underappreciated role of Ca(2+) release from intracellular repertoire in promoting plant disease resistance" |
| Keywords: | Brassica crop Ca2+-permeable channel Endoplasmic reticulum Plant immunity Plasmodiophora brassicae; |
| Notes: | "PubMed-not-MEDLINEWang, Feng-Zhu Li, Jian-Feng eng 32125004/National Natural Science Foundation of China/ Switzerland 2023/09/07 Stress Biol. 2023 Jul 22; 3(1):25. doi: 10.1007/s44154-023-00110-4" |
