| Title: | "Passive exposure of non-smokers to E-Cigarette aerosols: Sensory irritation, timing and association with volatile organic compounds" |
| Author(s): | Tzortzi A; Teloniatis S; Matiampa G; Bakelas G; Tzavara C; Vyzikidou VK; Vardavas C; Behrakis P; Fernandez E; Tack SHSP; |
| Address: | "'George D. Behrakis Research Lab' Hellenic Cancer Society, Athens, Greece; Institute of Public Health at the American College of Greece, Athens, Greece. 'George D. Behrakis Research Lab' Hellenic Cancer Society, Athens, Greece. Electronic address: steloniatis@gmail.com. 'George D. Behrakis Research Lab' Hellenic Cancer Society, Athens, Greece. Department of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Medical School, Athens, Greece. 'George D. Behrakis Research Lab' Hellenic Cancer Society, Athens, Greece; Institute of Public Health at the American College of Greece, Athens, Greece; Biomedical Research Foundation, Academy of Athens, Athens, Greece; Athens Medical Centre, Athens, Greece. Tobacco Control Unit, Department of Cancer Epidemiology and Prevention, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain; Tobacco Control Unit, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat (Barcelona), Spain; Department of Clinical Sciences, School of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Spain" |
| DOI: | 10.1016/j.envres.2019.108963 |
| ISSN/ISBN: | 1096-0953 (Electronic) 0013-9351 (Linking) |
| Abstract: | "AIM: The current study examined symptoms of irritation reported by non-smokers passively exposed to e-cigarette aerosols and their timing and association with the concentrations of volatile organic compounds (VOCs) produced. METHODS: 40 healthy non-smoking adults were exposed to e-cigarette aerosols for 30?ª+min in a 35?ª+m(3) room. Second-hand e-cigarette aerosol (SHA) was produced by an experienced e-cigarette user using a standardized topography and two resistance settings (exposure 0.5 Ohm and 1.5 Ohm), in addition to a control session (no emissions). PM(2.5) and PM(1.0) were continuously measured over the duration of exposure, while Volatile Organic Compounds (VOCs) were recorded at 0, 15 and 30?ª+min (t(0), t(15) and t(30)) of exposure. Each participant completed an irritation questionnaire at t(0), t(15,) t(30) of exposure and t(60) (30?ª+min post-exposure) on ocular, nasal, throat-respiratory symptoms of irritation and general complaints. Kruskal-Wallis H test for PM comparisons, repeated measures ANOVA for VOCs and Generalized Estimating Equations for symptoms of irritation and association with VOCs were used for statistical analysis. RESULTS: 20 males and 20 females, with a mean age of 24.6 years (SD?ª+=?ª+4.3) and exhaled CO?ª+?ª+0.05) while throat-respiratory symptoms were still significantly higher at t(60) (p?ª+=?ª+0.044). VOCs were significantly associated with reported nasal and throat-respiratory symptoms in both experimental sessions (p?ª+ |
| Keywords: | Adult Aerosols *Air Pollutants *Electronic Nicotine Delivery Systems Female Humans Male Non-Smokers *Tobacco Smoke Pollution *Volatile Organic Compounds/analysis/toxicity Young Adult Second-hand aerosol Sensory irritation Ultrafine particulates Volatile o; |
| Notes: | "MedlineTzortzi, Anna Teloniatis, Stephanie Matiampa, George Bakelas, Gerasimos Tzavara, Chara Vyzikidou, Vergina Konstantina Vardavas, Constantine Behrakis, Panagiotis Fernandez, Esteve eng Research Support, Non-U.S. Gov't Netherlands 2019/12/15 Environ Res. 2020 Mar; 182:108963. doi: 10.1016/j.envres.2019.108963. Epub 2019 Dec 3" |
