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Molecules

Title:		"Phytochemical Characterization of Rhus coriaria L. Extracts by Headspace Solid-Phase Micro Extraction Gas Chromatography, Comprehensive Two-Dimensional Liquid Chromatography, and Antioxidant Activity Evaluation"
Author(s):		Arena K; Trovato E; Cacciola F; Spagnuolo L; Pannucci E; Guarnaccia P; Santi L; Dugo P; Mondello L; Dugo L;
Address:		"Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, Italy. Department of Biomedical, Dental, Morphological and Functional Imaging Sciences, University of Messina, 98125 Messina, Italy. Department of Sciences and Technologies for Human and Environment, University Campus Bio-Medico of Rome, 00128 Rome, Italy. Department of Agriculture, Food Science and Environment (Di3A), University of Catania, 95124 Catania, Italy. Department of Agriculture and Forest Sciences (DAFNE), University of Tuscia, 01100 Viterbo, Italy. Chromaleont s.r.l., c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, Italy"
Journal Title:		Molecules
Year:		2022
Volume:		20220307
Issue:		5
Page Number:		-
DOI:		10.3390/molecules27051727
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"Rhus coriaria L. (Anacardiaceae), commonly known as sumac, has been used since ancient times for many different applications, and nowadays is used mostly as a spice obtained from its in the Mediterranean and the Middle ground fruits and employed for flavoring and garnishing food, predominantly Eastern regions. Traditionally, sumac has been also used in popular medicine for the treatment of many ailments including hemorrhoids, wound healing, diarrhea, ulcers, and eye inflammation. Sumac drupes are indeed rich in various classes of phytochemicals including organic acids, flavonoids, tannins, and others, which are responsible of their powerful antioxidant capacity, from which treatment of many common diseases such as cardiovascular disease, diabetes, and cancer could benefit. In this work we evaluated the influence of fruit ripeness, conservation, and processing. To this aim, a phytochemical characterization of six different samples of Rhus coriaria L. was carried out. Specifically, headspace solid-phase micro extraction gas chromatography coupled to mass spectrometry and comprehensive two-dimensional liquid chromatography coupled to photodiode array and mass spectrometry detection, were employed. A total of 263 volatile compounds, including terpene hydrocarbons, acids, and aldehydes, as well as 83 polyphenolic compounds, mainly gallic acid derivatives, were positively identified. All samples showed a significant antioxidant activity by means of oxygen radical absorbance capacity, in line with their polyphenolic content and composition. Such findings set a solid ground to support the utilization of this plant as an attractive target for novel nutraceutical approaches and for drug discovery"
Keywords:		*Rhus Gc LCxLC Rhus coriaria L.antioxidant activity mass spectrometry polyphenols sumac volatiles;
Notes:		"MedlineArena, Katia Trovato, Emanuela Cacciola, Francesco Spagnuolo, Ludovica Pannucci, Elisa Guarnaccia, Paolo Santi, Luca Dugo, Paola Mondello, Luigi Dugo, Laura eng Switzerland 2022/03/11 Molecules. 2022 Mar 7; 27(5):1727. doi: 10.3390/molecules27051727"