| Title: | Antibacterial Potent of Acetylated and Non-Acetylated Clove Bud Essential Oils and Their Main Compounds |
| Author(s): | Achraf A; Fatima Ezzahra M; Fatima Zahra M; Abdoullah B; Nour-Eddine C; Abdelhakim E; Jamal JE; Mohamed D; |
| Address: | "Laboratory of Organic Synthesis, Extraction and Valorization, Faculty of Sciences Ain Chock, Hassan II University of Casablanca, Morocco. Laboratory of Immunology & Biodiversity Faculty of Sciences Ain Chock, Hassan II University of Casablanca, Morocco. Laboratory of Organic Synthesis and Physico-Molecular Chemistry, Faculty of Sciences Semlalia Marrakech, Morocco" |
| ISSN/ISBN: | 1612-1880 (Electronic) 1612-1872 (Linking) |
| Abstract: | "Clove bud is a medicinal plant used traditionally in Asia for the treatment of various disease. Previously, Clove oil is a potential source of an antimicrobial compounds especially vis-a-vis bacterial pathogens. However, the compound responsible for this activity remains to be investigated. Essential oil (EO) clove, acetylated essential oil clove, eugenol, and acetyleugenol were evaluate as an antibacterial potential agent against Staphyloccocus aureus (SE), Escherichia coli (EC) and Pseudomonas aeruginosa (PA). Essential oil containing eugenol was extracted from buds of Eugenia caryophyllata commonly named clove (Syzygium aromaticum (L.) (Family Myrtaceae) by a simple hydrodistillation. The analysis of the essential oils (EOs) using gas chromatography-mass spectrometry (GC-MS) shows eugenol as the major constituent with 70.14 % of the total. The Eugenol was isolated from the EO using chemical treatment. Afterwards, the EO and eugenol were converted to acetylated EO and acetyleugenol, respectively using acetic anhydride. The antibacterial result revealed that all compounds showed a strong activity against the three strains. The Staphyloccocus aureus and Pseudomonas aeruginosa were extremely sensitive against eugenol with an inhibition diameters of 25 mm. The MIC values of eugenol versus S. aureus and P. aeruginosa were 0.58 and 2.32 mg/mL, respectively, while the MIB values were 2.32 mg/mL and 9.28 mg/mL" |
| Keywords: | "*Oils, Volatile/pharmacology/chemistry Eugenol/chemistry *Syzygium/chemistry Staphylococcus aureus Anti-Bacterial Agents/pharmacology Eugenia caryophyllata antibacterial essential oil eugenol isolation;" |
| Notes: | "MedlineAchraf, Abdou Fatima Ezzahra, Maaghloud Fatima Zahra, Moukhfi Abdoullah, Bimoussa Nour-Eddine, Chadli Abdelhakim, Elmakssoudi Jamal, Jamal Eddine Mohamed, Dakir eng Faculty of Science Ain Chock, Casablanca/ Switzerland 2023/03/10 Chem Biodivers. 2023 Apr; 20(4):e202201034. doi: 10.1002/cbdv.202201034. Epub 2023 Mar 17" |
