| Title: | "3-Ethyl-2,7-dimethyl octane, a testosterone dependent unique urinary sex pheromone in male mouse (Mus musculus)" |
| Address: | "Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India" |
| DOI: | 10.1016/j.anireprosci.2004.11.001 |
| ISSN/ISBN: | 0378-4320 (Print) 0378-4320 (Linking) |
| Abstract: | "A previous investigation revealed that urine from normal male mice contained five unique volatile constituents; namely: 3-cyclohexene-1-methanol (I); 3-amino triazole (II); 4-ethyl phenol (III); 3-ethyl-2,7-dimethyl octane (IV); 1-iodoundecane (V). The present study was designed to find out whether the production of these male specific urinary compounds was androgen-dependent. Urine of castrated and castrated plus testosterone-treated male mice was analyzed using gas chromatography linked mass spectrometry (GC-MS). Even though castrated male urine contained 10 detectable compounds, the five male specific compounds present in intact males were absent in castrated male mice urine. Only 3-ethyl-2,7-dimethyl octane (IV) reappeared following testosterone treatment into castrated males. Our earlier bioassay revealed that this compound was involved in attracting females. The present study concluded that this compound was a male specific volatile cue that acted as a releaser pheromone and its production was under the control of androgen" |
| Keywords: | Animals Gas Chromatography-Mass Spectrometry Male Mice Octanes/*urine Orchiectomy Sex Attractants/*urine Testosterone/administration & dosage/*physiology Volatilization; |
| Notes: | "MedlineAchiraman, S Archunan, G eng Research Support, Non-U.S. Gov't Netherlands 2005/05/12 Anim Reprod Sci. 2005 Jun; 87(1-2):151-61. doi: 10.1016/j.anireprosci.2004.11.001. Epub 2005 Jan 7" |
