| Title: | Predicted environmental concentrations of cocaine and benzoylecgonine in a model environmental system |
| Author(s): | Domenech X; Peral J; Munoz I; |
| Address: | "Departament de Quimica, Universitat Autonoma de Barcelona, 08193 Cerdanyola del Valles, Spain. xavier.domenech@uab.cat" |
| DOI: | 10.1016/j.watres.2009.08.033 |
| ISSN/ISBN: | 1879-2448 (Electronic) 0043-1354 (Linking) |
| Abstract: | "A Mackay-type level II fugacity model has been used to predict the behaviour and final concentrations of cocaine (COC) and its main metabolite benzoylecgonine (BE) in a regional environmental system defined according to the European guidelines on Risk Assessment. The model takes into account the initial COC intake, partial degradation of the parent compound to BE, treatment of wastewater and environmental fate of these substances. Predicted environmental concentrations (PECs) lie in the ngL(-1) level, with the exception of the air compartment, where the concentrations are negligible. PECs in the water phase are in accordance with measured experimental concentrations in different European rivers. This case study shows that a simple level II fugacity model is suitable enough for modelling the environmental fate of high water soluble and low volatile organic compounds such as pharmaceuticals and personal care products" |
| Keywords: | "Cocaine/*analogs & derivatives/*analysis Environmental Monitoring/*methods Environmental Pollutants/*analysis Forecasting *Models, Chemical;" |
| Notes: | "MedlineDomenech, Xavier Peral, Jose Munoz, Ivan eng Research Support, Non-U.S. Gov't England 2009/09/29 Water Res. 2009 Dec; 43(20):5236-42. doi: 10.1016/j.watres.2009.08.033. Epub 2009 Aug 29" |
