| Title: | The mechanism for microsporidian parasite suppression of the hindgut bacteria of the migratory locust Locusta migratoria manilensis |
| Author(s): | Tan SQ; Zhang KQ; Chen HX; Ge Y; Ji R; Shi WP; |
| Address: | "Department of Entomology, China Agricultural University, Beijing, China. College of Life Science, Xinjiang Normal University, Urumchi, China" |
| ISSN/ISBN: | 2045-2322 (Electronic) 2045-2322 (Linking) |
| Abstract: | "Locusts aggregate into bands of nymphs and swarms of adults that can pose a major threat to crop. Previous studies have shown that infection by the microsporidian parasite Paranosema locustae prevents locust aggregation behavior and we show that gut bacteria, which produce components of locust aggregation pheromones, are substantially reduced in locusts infected with P. locustae. We found that P. locustae could reduce the diversity, abundance and community composition of Locusta migratoria's gut bacteria. The parasite infection was also shown to interrupt the peroxidase activity of locust hindgut. Genome-wide expression analysis showed that the parasite infection suppressed peroxidase mRNA relative expression of locust hindgut, but had no effects on attacin expression and superoxide dismutase at 16 d post-inoculation with 20,000 P. locustae spores. Our findings reveal the mechanisms by which P. locustae impairs bacterial diversity and community structure of Locusta migratoria's gut bacteria" |
| Keywords: | "Animals *Antibiosis Bacteria/classification/*drug effects/growth & development Behavior, Animal Biodiversity Biological Control Agents/pharmacology Gastrointestinal Microbiome/*drug effects/physiology Gene Expression Regulation Host-Pathogen Interactions;" |
| Notes: | "MedlineTan, Shu-Qian Zhang, Kai-Qi Chen, Hong-Xing Ge, Yang Ji, Rong Shi, Wang-Peng eng Research Support, Non-U.S. Gov't England 2015/11/28 Sci Rep. 2015 Nov 27; 5:17365. doi: 10.1038/srep17365" |
