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World Allergy Organ J

Title:		International expert consensus on the management of allergic rhinitis (AR) aggravated by air pollutants: Impact of air pollution on patients with AR: Current knowledge and future strategies
Author(s):		Naclerio R; Ansotegui IJ; Bousquet J; Canonica GW; D'Amato G; Rosario N; Pawankar R; Peden D; Bergmann KC; Bielory L; Caraballo L; Cecchi L; Cepeda SAM; Chong Neto HJ; Galan C; Gonzalez Diaz SN; Idriss S; Popov T; Ramon GD; Ridolo E; Rottem M; Songnuan W; Rouadi P;
Address:		"Johns Hopkins School of Medicine, Baltimore, MD, USA. Department of Allergy & Immunology, Hospital Quironsalud Bizkaia- Bilbao, Spain. INSERM U 1168, VIMA: Ageing and Chronic Diseases Epidemiological and Public Health Approaches, Villejuif, France. University Versailles St-Quentin-en-Yvelines, France. Allergy-Centre-Charite, Charite-Universita tsmedizin Berlin, Berlin, Germany. Humanitas University & Research Hospital, Milano, Italy. Division of Respiratory and Allergic Diseases, High Specialty Hospital A. Cardarelli, Napoli, Italy; School of Specialization in Respiratory Diseases University Federico II Naples, Italy. Pediatric Respiratory Medicine Division, Complexo Hospital de Clinicas, UFPR, Curitiba, Brazil. Dept. of Pediatrics, Nippon Medical School, Tokyo, Japan. UNC Center for Environmental Medicine, Asthma, and Lung Biology; Division of Allergy, Immunology and Rheumatology, Dpt. of Pediatrics UNS School of Medicine, USA. Medicine & Ophthalmology Hackensack Meridian School of Medicine at Seton Hall University Nutley, New Jersey, USA. Institute for Immunological Research, University of Cartagena, Cartagena de Indias, Colombia. Centre de Bioclimatology, University de Florence, Florence, Italy. SOS Allergy and Immunology, Prato - USL Toscana Centro, Italy. Fundacion Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia. Federal University of Parana, Brazil. Department of Botany, Ecology and Plant Physiology, University of Cordoba, Spain. San Francisco Centro de Especialistas Medicos Monterrey NL, Mexico. Department of Otolaryngology- Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon. Alexander's University Hospital Clinic of Allergy & Asthma, Bulgaria. Alergia e Inmunologia, Hospital Italiano Regional del Sur, Bahia Blanca-Buenos Aires, Argentina. Department of Clinical and Experimental Medicine, Universita; di Parma, Parma, Italy. Allergy Asthma and Immunology, Emek Medical Center, Afula, Israel. Rappaport Faculty of Medicine Technion, Israel Institute of Technology, Haifa, Israel. Department of Plant Science, Faculty of Science, Mahidol University, Bangkok, Thailand. Systems Biology of Diseases Research Unit, Faculty of Science, Mahidol University, Bangkok, Thailand"
Journal Title:		World Allergy Organ J
Year:		2020
Volume:		20200403
Issue:		3
Page Number:		100106 -
DOI:		10.1016/j.waojou.2020.100106
ISSN/ISBN:		1939-4551 (Print) 1939-4551 (Electronic) 1939-4551 (Linking)
Abstract:		"Allergic rhinitis affects the quality of life of millions of people worldwide. Air pollution not only causes morbidity, but nearly 3 million people per year die from unhealthy indoor air exposure. Furthermore, allergic rhinitis and air pollution interact. This report summarizes the discussion of an International Expert Consensus on the management of allergic rhinitis aggravated by air pollution. The report begins with a review of indoor and outdoor air pollutants followed by epidemiologic evidence showing the impact of air pollution and climate change on the upper airway and allergic rhinitis. Mechanisms, particularly oxidative stress, potentially explaining the interactions between air pollution and allergic rhinitis are discussed. Treatment for the management of allergic rhinitis aggravated by air pollution primarily involves treating allergic rhinitis by guidelines and reducing exposure to pollutants. Fexofenadine a non-sedating oral antihistamine improves AR symptoms aggravated by air pollution. However, more efficacy studies on other pharmacological therapy of coexisting AR and air pollution are currently lacking"
Keywords:		"AER, Allergic eosinophilic rhinitis AP, Activator protein AR, Allergic rhinitis ARE, Antioxidant response element Air pollutants Air pollution Allergic rhinitis Antioxidant enzymes CFS, Chronic fatigue syndrome CO, Carbon monoxide COPD, Chronic obstructiv;"
Notes:		"PubMed-not-MEDLINENaclerio, Robert Ansotegui, Ignacio J Bousquet, Jean Canonica, G Walter D'Amato, Gennaro Rosario, Nelson Pawankar, Ruby Peden, David Bergmann, Karl-Christian Bielory, Leonard Caraballo, Luis Cecchi, Lorenzo Cepeda, S Alfonso M Chong Neto, Herberto Jose Galan, Carmen Gonzalez Diaz, Sandra N Idriss, Samar Popov, Todor Ramon, German D Ridolo, Erminia Rottem, Menachem Songnuan, Wisuwat Rouadi, Philip eng P30 ES010126/ES/NIEHS NIH HHS/ 2020/04/08 World Allergy Organ J. 2020 Apr 3; 13(3):100106. doi: 10.1016/j.waojou.2020.100106. eCollection 2020 Mar"