« Previous AbstractDevelopment of an enzyme immunoassay to measure urinary and faecal 5alpha-androst-16-en-3-one in pigs    Next AbstractCuelure but not zingerone make the sex pheromone of male Bactrocera tryoni (Tephritidae: Diptera) more attractive to females »

Front Plant Sci

Title:		AromaDb: A Database of Medicinal and Aromatic Plant's Aroma Molecules With Phytochemistry and Therapeutic Potentials
Author(s):		Kumar Y; Prakash O; Tripathi H; Tandon S; Gupta MM; Rahman LU; Lal RK; Semwal M; Darokar MP; Khan F;
Address:		"Department of Metabolic and Structural Biology, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Department of Process Chemistry and Chemical Engineering, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Department of Analytical Chemistry, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Department of Plant Biotechnology, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Department of Plant Breeding, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Information and Communication Technology Lab, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Department of Molecular Bioprospection, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, San Diego, CA, United States"
Journal Title:		Front Plant Sci
Year:		2018
Volume:		20180813
Issue:
Page Number:		1081 -
DOI:		10.3389/fpls.2018.01081
ISSN/ISBN:		1664-462X (Print) 1664-462X (Electronic) 1664-462X (Linking)
Abstract:		"In traditional, herbal medicine, and aromatherapy, use of essential oils and their aroma compounds have been known since long, for the management of various human diseases. The essential oil is a mixture of highly complex, naturally occurring volatile aroma compounds synthesized by medicinal and aromatic plants as secondary metabolites. Essential oils widely used in pharmaceutical, cosmetic, sanitary, food industry and agriculture for their antibacterial, antiviral, antifungal, antiparasitic, insecticidal, anticancer, neuroprotective, psychophysiological, and anti-aging activities. Moreover, volatile aroma compounds comprise a chemically diverse class of low molecular weight organic compounds with significant vapor pressure. However, aroma compounds produced by plants, mainly attract pollinators, seed dispersers and provide defense against pests or pathogens. However, in humans, about 300 active olfactory receptor genes are involved to detect thousands of different aroma compounds and modulates expression of different metabolic genes regulating human psychophysiological activity, brain function, pharmacological signaling, and therapeutic potential. Keeping in mind this importance, present database, namely, AromaDb (http://bioinfo.cimap.res.in/aromadb/) covers information of plant varieties/chemotypes, essential oils, chemical constituents, GC-MS profile, yield variations due to agro-morphological parameters, trade data, aroma compounds, fragrance type, and bioactivity details. The database includes 1,321 aroma chemical structures, bioactivities of essential oil/aroma compounds, 357 fragrance type, 166 commercially used plants, and their high yielding 148 varieties/chemotypes. Also includes calculated cheminformatics properties related to identification, physico-chemical properties, pharmacokinetics, toxicological, and ecological information. Also comprises interacted human genes affecting various diseases related cell signaling pathways correlating the use of aromatherapy. This database could be a useful resource to the plant's growers/producers, an aroma/fragrance industrialist, health professionals, and researchers exploring the potential of essential oils and aroma compounds in the development of novel formulations against human diseases"
Keywords:		aroma aromatic bioactivity chemotypes essential oils medicinal molecule plants;
Notes:		"PubMed-not-MEDLINEKumar, Yogesh Prakash, Om Tripathi, Himanshu Tandon, Sudeep Gupta, Madan M Rahman, Laiq-Ur Lal, Raj K Semwal, Manoj Darokar, Mahendra Pandurang Khan, Feroz eng Switzerland 2018/08/29 Front Plant Sci. 2018 Aug 13; 9:1081. doi: 10.3389/fpls.2018.01081. eCollection 2018"