| Title: | Structural investigations of pyridin-4-yl indolizine modified beta-cyclodextrin derivatives as fluorescent chemosensors for organic guest molecules |
| Author(s): | Delattre F; Woisel P; Bria M; Surpateanu G; |
| Address: | "Laboratoire de Synthese Organique et Environnement, Universite du Littoral Cote d'Opale, 145 avenue M. Schumann, F-59140 Dunkerque, France. delattre@univ-littoral.fr" |
| DOI: | 10.1016/j.carres.2005.05.001 |
| ISSN/ISBN: | 0008-6215 (Print) 0008-6215 (Linking) |
| Abstract: | "In order to investigate the substituent effects on their conformations and spectroscopic properties, a series of pyridin-4-ylindolizine modified beta-cyclodextrin derivatives were studied by 2D NMR (ROESY spectra) in D2O, circular dichroism, and fluorescence spectroscopy. It was found that the linked indolizin-beta-cyclodextrin compounds exhibited two types of conformations, as a function of the substituent, in which fluorescent moieties formed either an intramolecular complex or were not included in the hydrophobic cavity of the macrocycle. Under addition of organic guest species in a phosphate buffer at neutral pH, the variation of emission fluorescence intensity showed that these compounds are of significance for detection of volatile organic molecules and adamantane derivatives and might be used as molecular chemosensor" |
| Keywords: | "Circular Dichroism Fluorescence Hydrogen-Ion Concentration Indolizines/*chemistry Magnetic Resonance Spectroscopy Molecular Structure Pyridines/*chemistry Spectrometry, Fluorescence Temperature beta-Cyclodextrins/*chemistry;" |
| Notes: | "MedlineDelattre, Francois Woisel, Patrice Bria, Marc Surpateanu, Gheorghe eng Netherlands 2005/06/02 Carbohydr Res. 2005 Jul 25; 340(10):1706-13. doi: 10.1016/j.carres.2005.05.001" |
