« Previous AbstractFunctional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras    Next AbstractAntiviral Activity of the Propylamylatin(TM) Formula against the Novel Coronavirus SARS-CoV-2 In Vitro Using Direct Injection and Gas Assays in Virus Suspensions »

Trends Genet

Title:		Mating in mushrooms: increasing the chances but prolonging the affair
Author(s):		Brown AJ; Casselton LA;
Address:		"Molecular Pharmacology, GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, SG1 2NY, Stevenage, UK"
Journal Title:		Trends Genet
Year:		2001
Volume:		17
Issue:		7
Page Number:		393 - 400
DOI:		10.1016/s0168-9525(01)02343-5
ISSN/ISBN:		0168-9525 (Print) 0168-9525 (Linking)
Abstract:		"Finding a compatible mating partner is an essential step in the life cycle of most sexually reproducing organisms. Fungi have two or more mating types, and only cells of different mating type combine to produce diploid cells. In mushrooms, this is taken to extremes, with the occurrence of many thousands of mating types. But, having gone to such extraordinary lengths to ensure that almost any two mushroom mycelia in the wild can mate, cell fusion is not followed by nuclear fusion and true diploidy. Instead, the fused cells form a characteristic mycelium, known as the dikaryon, in which haploid nuclei are paired but actively prevented from fusing. The mating-type genes, which encode pheromones, pheromone receptors and homeodomain transcription factors, have crucial roles in regulating the complex developmental programme by which the dikaryon is formed"
Keywords:		"Basidiomycota/cytology/genetics/*physiology Cell Fusion Gene Expression Regulation, Fungal Genes, Fungal/genetics/physiology Genes, Mating Type, Fungal Homeodomain Proteins/genetics/metabolism Pheromones/chemistry/genetics/metabolism Receptors, Cell Surfa;"
Notes:		"MedlineBrown, A J Casselton, L A eng Research Support, Non-U.S. Gov't Review England 2001/06/22 Trends Genet. 2001 Jul; 17(7):393-400. doi: 10.1016/s0168-9525(01)02343-5"