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Sensors (Basel)

Title:		Chemoresistive gas sensors for the detection of colorectal cancer biomarkers
Author(s):		Malagu C; Fabbri B; Gherardi S; Giberti A; Guidi V; Landini N; Zonta G;
Address:		"Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. malagu@fe.infn.it. Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. fbbbbr@unife.it. Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. gherardi@fe.infn.it. Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. giberti@fe.infn.it. Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. guidi@fe.infn.it. Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. nicolo.landini@student.unife.it. Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy. giulia.zonta@unife.it"
Journal Title:		Sensors (Basel)
Year:		2014
Volume:		20141013
Issue:		10
Page Number:		18982 - 18992
DOI:		10.3390/s141018982
ISSN/ISBN:		1424-8220 (Electronic) 1424-8220 (Linking)
Abstract:		"Numerous medical studies show that tumor growth is accompanied by protein changes that may lead to the peroxidation of the cell membrane with consequent emission of volatile organic compounds (VOCs) by breath or intestinal gases that should be seen as biomarkers for colorectal cancer (CRC). The analysis of VOCs represents a non-invasive and potentially inexpensive preliminary screening technique. An array of chemoresistive gas sensors based on screen-printed metal oxide semiconducting films has been selected to discriminate gases of oncological interest, e.g., 1-iodononane and benzene, widely assumed to be biomarkers of colorectal cancer, from those of interference in the gut, such as methane and nitric oxide"
Keywords:		"Benzene/*isolation & purification Biomarkers, Tumor/isolation & purification Biosensing Techniques/*methods Colorectal Neoplasms/*diagnosis/metabolism/pathology Gas Chromatography-Mass Spectrometry Gases/isolation & purification/metabolism Humans Volatile;"
Notes:		"MedlineMalagu, Cesare Fabbri, Barbara Gherardi, Sandro Giberti, Alessio Guidi, Vincenzo Landini, Nicolo Zonta, Giulia eng Switzerland 2014/10/15 Sensors (Basel). 2014 Oct 13; 14(10):18982-92. doi: 10.3390/s141018982"