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Molecules

Title:		Effect of Volatile Organic Chemicals in Chrysanthemum indicum Linne on Blood Pressure and Electroencephalogram
Author(s):		Kim DS; Goo YM; Cho J; Lee J; Lee DY; Sin SM; Kil YS; Jeong WM; Ko KH; Yang KJ; Kim YG; Kim SG; Kim K; Kim YJ; Kim JK; Shin EC;
Address:		"Department of Food Science, Gyeongnam National University of Science and Technology, Jinju, Gyeongnam 52725, Korea. kim94dasom@naver.com. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. dudals1109@naver.com. Department of Food Science, Gyeongnam National University of Science and Technology, Jinju, Gyeongnam 52725, Korea. aacho7@daum.net. Department of Food Science, Gyeongnam National University of Science and Technology, Jinju, Gyeongnam 52725, Korea. tracylee0911@gmail.com. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. 7560112@naver.com. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. sksskdi714@hanmail.net. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. miohkil@naver.com. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. wonmin5618@gmail.com. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. kosajang83@naver.com. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. yang2229@gnherb.or.kr. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. koreanol@hanmail.net. Gyeongnam Oriental Medicinal Herb Institute, Sancheong 52215, Korea. sen600@hanmail.net. Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. iames@kaist.ac.kr. Department of Food and Biotechnology, Korea University, Sejong 30019, Korea. yk46@korea.ac.kr. School of Human Environmental Sciences, University of Arkansas, Fayetteville, AR 72701, USA. jkk003@uark.edu. Department of Food Science, Gyeongnam National University of Science and Technology, Jinju, Gyeongnam 52725, Korea. eshin@gntech.ac.kr"
Journal Title:		Molecules
Year:		2018
Volume:		20180817
Issue:		8
Page Number:		-
DOI:		10.3390/molecules23082063
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"This study identified the volatile organic compounds in the essential oils that are extracted from Chrysanthemum indicum Linne (C. indicum Linne) and investigated the effects of the inhalation of these compounds. We detected a total of 41 volatile organic compounds, including 32 hydrocarbons, four acids, three alcohols, two ketones, and one aldehyde. In a sniffing test, seven types of volatile organic compounds were identified. Furthermore, the volatile organic compounds in C. indicum Linne that were identified were found to be derived from 1,8-cineole and camphor. After inhalation of the essential oils, the subjects' systolic blood pressure and heart rate decreased. This indicates that inhalation of the essential oils extracted from C. indicum Linne provides mental and physical relaxation. We examined the changes in electroencephalogram findings that are observed after C. indicum Linne essential oil inhalation. An increase in theta and alpha waves, which usually appear during relaxation, as well as a decrease in beta and gamma waves, which appear during brain activity such as excessive attention, were noted. These results indicate that C. indicum Linne essential oil inhalation helps to reduce blood pressure and may provide mental and physical relaxation"
Keywords:		"Administration, Inhalation Blood Pressure/*drug effects Brain Waves/drug effects Chrysanthemum/*chemistry *Electroencephalography Female Heart Rate Humans Male Oils, Volatile/chemistry/pharmacology Volatile Organic Compounds/*chemistry/*pharmacology Chrys;"
Notes:		"MedlineKim, Da-Som Goo, Young-Min Cho, Jinju Lee, Jookyeong Lee, Dong Yeol Sin, Seung Mi Kil, Young Sook Jeong, Won Min Ko, Keon Hee Yang, Ki Jeung Kim, Yun Geun Kim, Sang Gon Kim, Kiseong Kim, Young Jun Kim, Jae Kyeom Shin, Eui-Cheol eng Switzerland 2018/08/22 Molecules. 2018 Aug 17; 23(8):2063. doi: 10.3390/molecules23082063"