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Int J Food Sci Nutr

Title:		Activity of 30 different cheeses on cholesterol plasma levels and Oxidative Balance Risk Index (OBRI) in a rat model
Author(s):		Cornelli U; Bondiolotti G; Battelli G; Zanoni G; Finco A; Recchia M;
Address:		"Loyola University School of Medicine , Chicago, IL , USA"
Journal Title:		Int J Food Sci Nutr
Year:		2015
Volume:		20150330
Issue:		4
Page Number:		383 - 390
DOI:		10.3109/09637486.2015.1024205
ISSN/ISBN:		1465-3478 (Electronic) 0963-7486 (Linking)
Abstract:		"BACKGROUND: Cheese is considered to increase the total cholesterol levels (CH) due to the high-saturated fat content. New models are needed to measure the relationship between cholesterol and cheese. METHODS: Thirty different cheeses produced in Val Brembana, Italy ('furmai da mut', 'caprino' and 'stracchino'), were added to the diet of 30 groups of 4 rats. Cheeses were analyzed to differentiate the volatile organic compounds (VOCs) and the cholesterol content (Ch(f)). The body weight, CH, urine volume and oxidative balance were measured. Three new indexes in relation to CH were calculated: OI (oxidative index), PI (protective index) and OBRI (oxidative balance risk index). RESULTS: None of the cheeses increased CH. Some of the 'furmai de mut' were significantly decreasing CH and improved the oxidative balance. Ch(f) was not affecting the CH levels in plasma. In terms of VOCs, the acetic acid content was correlated (p < 0.05) with the CH reduction and PI improvement. OBRI was reduced mainly in the 'stracchino group'. CONCLUSIONS: The model shows that some cheese can reduce significantly CH levels and improve the antioxidant capacity"
Keywords:		"Animals Body Weight/drug effects/physiology *Cheese Cholesterol/*blood Diet/*methods Italy Male Models, Animal Oxidation-Reduction Oxidative Stress/drug effects/*physiology Rats Rats, Wistar Risk Volatile Organic Compounds/analysis Cheese Obri cholesterol;"
Notes:		"MedlineCornelli, Umberto Bondiolotti, Gianpietro Battelli, Giovanna Zanoni, Giuseppe Finco, Annarosa Recchia, Martino eng Research Support, Non-U.S. Gov't England 2015/03/31 Int J Food Sci Nutr. 2015; 66(4):383-90. doi: 10.3109/09637486.2015.1024205. Epub 2015 Mar 30"