| Title: | Rhabdomyolysis with acute tubular necrosis following occupational inhalation of thinners |
| Address: | "Division of Occupational Medicine, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa" |
| ISSN/ISBN: | 1471-8405 (Electronic) 0962-7480 (Linking) |
| Abstract: | "Thinners are mixtures of organic solvents commonly containing toluene, xylene, acetone, hexane, benzene and methyl isobutyl ketone. This report describes a case of rhabdomyolysis with acute tubular necrosis and renal failure, most likely attributable to toluene, following occupational exposure to thinners while cleaning a steel water tank. These adverse health effects have previously been reported following acute poisoning or intentional inhalation by drug abusers, but rarely in the occupational setting. Poor working conditions, lack of health and safety training and delayed treatment contributed to the onset and severity of the patient's complications. This case emphasizes the need for strict control measures, including adequate ventilation, training on working in confined spaces, appropriate personal protective equipment and emergency rescue procedures in such settings. In addition, rhabdomyolysis, acute tubular necrosis and renal failure should be added to safety data material as possible complications of excessive inhalation of thinners" |
| Keywords: | "Acute Kidney Injury/*chemically induced/diagnosis Adult Confined Spaces Humans Inhalation Exposure Kidney Tubular Necrosis, Acute/*chemically induced/diagnosis Male Occupational Exposure Rhabdomyolysis/*chemically induced/diagnosis Solvents/*poisoning Sou;" |
| Notes: | "MedlineNgajilo, D Ehrlich, R eng Case Reports England 2017/05/10 Occup Med (Lond). 2017 Jul 1; 67(5):401-403. doi: 10.1093/occmed/kqx048" |
