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Tsitologiia

Title:		[Chromosomal abnormalities and spleenocyte production in laboratory mouse males after exposure to stress chemosignals]
Author(s):		Daev EV; Surinov BP; Dukel'skaia AV; Marysheva TM;
Address:
Journal Title:		Tsitologiia
Year:		2007
Volume:		49
Issue:		8
Page Number:		696 - 701
DOI:
ISSN/ISBN:		0041-3771 (Print) 0041-3771 (Linking)
Abstract:		"Activity of antibody producing spleenocytes and chromosome stability in bone marrow cells from laboratory mouse males of CBA strain after exposure to different chemosignals excreted by stressed or irradiated syngeneic donors was studied. It has been shown that the exposure of the recipient males to volatiles from donor males (stressed by swimming) decreases quantity of antibody-producing cells in 1, 3 and 10 days after the treatment. The same exposure increased the chromosome aberrations level in dividing bone marrow cells from CBA recipients in 1 day after the treatment. Similar changes were observed in 24 h after exposure to volatiles of irradiated donors or to synthetic mouse pheromone, 2,5-dimethylpyrazine. Possible mechanisms of chemosignals effect on the immune system are discussed"
Keywords:		"Animals Bone Marrow/*pathology/radiation effects Bone Marrow Cells/*pathology/radiation effects *Chromosome Aberrations *Gamma Rays Lymphocyte Count Lymphocytes/*immunology Male Mice Mice, Inbred CBA Pheromones/metabolism/*pharmacology Plasma Cells/immuno;"
Notes:		"MedlineDaev, E V Surinov, B P Dukel'skaia, A V Marysheva, T M rus English Abstract Research Support, Non-U.S. Gov't Russia (Federation) 2007/10/12 Tsitologiia. 2007; 49(8):696-701"