Bedoukian   RussellIPM   RussellIPM   Piezoelectric Micro-Sprayer


Home
Animal Taxa
Plant Taxa
Semiochemicals
Floral Compounds
Semiochemical Detail
Semiochemicals & Taxa
Synthesis
Control
Invasive spp.
References

Abstract

Guide

Alphascents
Pherobio
InsectScience
E-Econex
Counterpart-Semiochemicals
Print
Email to a Friend
Kindly Donate for The Pherobase

« Previous AbstractPlant Volatiles: Going 'In' but not 'Out' of Trichome Cavities    Next AbstractPheromone biosynthesis in bark beetles »

Mol Cell Endocrinol


Title:"Structure and juvenile hormone-mediated regulation of the HMG-CoA reductase gene from the Jeffrey pine beetle, Dendroctonus jeffreyi"
Author(s):Tittiger C; Barkawi LS; Bengoa CS; Blomquist GJ; Seybold SJ;
Address:"Department of Biochemistry, Mail Stop 330, University of Nevada, Reno 89557, USA. crt@unr.edu"
Journal Title:Mol Cell Endocrinol
Year:2003
Volume:199
Issue:1-Feb
Page Number:11 - 21
DOI: 10.1016/s0303-7207(02)00358-1
ISSN/ISBN:0303-7207 (Print) 0303-7207 (Linking)
Abstract:"In several pine bark beetle species, juvenile hormone (JH) III regulated 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-R) gene expression has an important role in monoterpenoid pheromone production in males. We investigated the structure and regulated expression of the HMG-R gene (HMG-R) in the Jeffrey pine beetle, Dendroctonus jeffreyi. cDNA and genomic sequences were recovered using a combination of library screening and PCR. The transcribed portion of the gene spans 9.8 kb and is interrupted by 13 introns. When compared to vertebrate HMG-Rs, the distribution of intron sites suggests a functional role for those in the 5' untranslated region and membrane anchor domains. Northern blots show that topically applied JH III stimulates HMG-R expression up to 30-fold in male D. jeffreyi, compared to untreated insects, in both a dose- and time-dependent manner. There was no increase in expression levels in similarly treated female insects. The expression pattern is consistent with the production of monoterpenoid pheromone components in male D. jeffreyi, and suggests the utility of the system as a new tool for studying the mechanism of JH action"
Keywords:"5' Untranslated Regions Animals Base Sequence Coleoptera/*enzymology Dose-Response Relationship, Drug Female Gene Expression Regulation/*drug effects Glycosylphosphatidylinositols/genetics Hydroxymethylglutaryl CoA Reductases/biosynthesis/*genetics Intron;"
Notes:"MedlineTittiger, Claus Barkawi, Lana S Bengoa, Cody S Blomquist, Gary J Seybold, Steven J eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Ireland 2003/02/13 Mol Cell Endocrinol. 2003 Jan 31; 199(1-2):11-21. doi: 10.1016/s0303-7207(02)00358-1"

 
Back to top
 
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024 The Pherobase - Extensive Database of Pheromones and Semiochemicals. Ashraf M. El-Sayed.
Page created on 26-12-2024