| Title: | Toxicity risks of occupational exposure in 3D printing and bioprinting industries: A systematic review |
| Author(s): | Mohammadian Y; Nasirzadeh N; |
| Address: | "Department of Occupational Health Engineering, 48432Faculty of Health, Tabriz University of Medical Science, Tabriz, Iran. Department of Occupational Health Engineering, School of Public Health, 48439Tehran University of Medical Science, Tehran, Iran" |
| DOI: | 10.1177/07482337211031691 |
| ISSN/ISBN: | 1477-0393 (Electronic) 0748-2337 (Linking) |
| Abstract: | "3-Dimensional (3D) printing and bioprinting are the new technologies. In 3D printing, synthetic polymers such as acrylonitrile, butadiene, and styrene, polylactic acid, nylon, and some metals are used as feedstocks. During 3D printing, volatile organic compounds (VOCs) and nanoparticles can be released. In the bioprinting process, natural polymers are most commonly used. All of these materials have direct and indirect toxic effects in exposed people. Therefore, the aim of this study was to provide a comprehensive review of toxicity risks due to occupational exposure to pollutants in the 3D printing and bioprinting industries. The Cochrane review method was used as a guideline for systematic review. Articles were searched in the databases including PubMed, Scopus, Web of Science, and Google Scholar. This systematic review showed that VOCs and ultra-fine particles are often released in fused deposition modeling and selective laser sintering, respectively. Asthma, chronic obstructive pulmonary disease, allergic rhinitis, and DNA damage were observed in occupational exposure to synthetic polymers. Metal nanoparticles can induce adverse health effects on the respiratory and nervous systems. This study emphasized the need to further study the toxicity of 3D printing and bioprinting-induced air pollutants. Also, consideration of safety and health principles is necessary in 3D printing and bioprinting workplaces" |
| Keywords: | Air Pollutants/adverse effects/analysis Bioprinting/*methods DNA Damage/drug effects Humans Inflammation Mediators/metabolism Neuromuscular Diseases/*chemically induced Occupational Exposure/*adverse effects/*analysis Particulate Matter/adverse effects/an; |
| Notes: | "MedlineMohammadian, Yousef Nasirzadeh, Nafiseh eng Systematic Review England 2021/08/18 Toxicol Ind Health. 2021 Sep; 37(9):573-584. doi: 10.1177/07482337211031691. Epub 2021 Aug 17" |
